Il17c

Gene Symbol Il17c
Entrez Gene 234836
Alt Symbol IL-17C
Species Mouse
Gene Type protein-coding
Description interleukin 17C
Other Description cytokine CX2|interleukin-17C
Swissprots A6H6F0 Q8K4C5
Accessions CAL40893 EDL11677 EDL11678 Q8K4C5 AF458061 AAM77565 BC145853 AAI45854 NM_145834 NP_665833
Function Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NFKB and MAPK pathways. Acts synergically with IL22, TNF and IL1B in inducing antibacterial peptides. May have protective function by maintaining epithelial homeostasis after an inflammatory challenge, such as that caused in the intestine by dextran sulfate sodium in a colitis model. May also promote an inflammatory phenotype, such as skin in a psoriasis model. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases, such as autoimmune encephalitis. {ECO:0000269|PubMed:21982598, ECO:0000269|PubMed:21993848, ECO:0000269|PubMed:21993849}.
Subcellular Location Secreted {ECO:0000305}.
Tissue Specificity Expressed by epithelial cells after bacterial challenge. Low expression, if any, in lymphocytes. {ECO:0000269|PubMed:21993848}.

Recombinant Mouse IL-17C - 2306-ML-025 from R&D Systems

Category Protein
Source E. coli-derived, His15-Gln194, with an N-terminal Met

Recombinant Mouse IL-17C, CF - 2306-ML-025/CF from R&D Systems

Category Protein
Source E. coli-derived, His15-Gln194, with an N-terminal Met

IL17C protein (Mouse) - 30R-2174 from Fitzgerald

Category Protein
Source Insect cells
Species Mouse

Mouse Interleukin 17C Protein - abx067477 from Abbexa

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Il17c, Met-tagged - Il17c-833M from Creative Biomart

Category Protein
Source E. coli
Species Mouse

Recombinant Mouse Interleukin 17C, His-tagged - Il17c-290M from Creative Biomart

Category Protein
Source Insect cell .

Recombinant Mouse Interleukin 17C Carrier-Free, His-tagged - Il17c-292M from Creative Biomart

Category Protein
Source Insect cell .

Recombinant Interleukin 17C (IL17C) - RPD347Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Interleukin 17C (IL17C) - RPD347Mu02 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse IL-17C Protein, CF - 2306-ML/CF from R&D Systems

Category Protein
Prices $329.00
Sizes 25 µg
Source E. coli -derived His15-Gln194, with an N-terminal Met
Species Mouse

Recombinant Mouse IL-17C Protein - 2306-ML from R&D Systems

Category Protein
Prices $329.00
Sizes 25 µg
Source E. coli -derived His15-Gln194, with an N-terminal Met
Species Mouse

Interleukin 17C (IL17C) - RPU142253 from Biomatik

Category Protein
Prices $240.90, $481.80, $722.70
Sizes 10 µg, 50 µg, 100 µg
Source E.coli
Species Mouse

Recombinant Interleukin 17C (IL17C) - RPU42253 from Biomatik

Category Protein
Prices $193.00, $394.00, $603.00, $718.32
Sizes 10 µg, 50 µg, 100 µg, 200 µg
Source E.coli
Species Mouse

IL17C Recombinant Protein (OPCD04287) - OPCD04287 from Aviva Systems Biology

Category Protein
Source E.coli
Species Mouse
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