Il17c

Gene Symbol	Il17c
Entrez Gene	234836
Alt Symbol	IL-17C
Species	Mouse
Gene Type	protein-coding
Description	interleukin 17C
Other Description	cytokine CX2|interleukin-17C
Swissprots	A6H6F0 Q8K4C5
Accessions	CAL40893 EDL11677 EDL11678 Q8K4C5 AF458061 AAM77565 BC145853 AAI45854 NM_145834 NP_665833
Function	Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NFKB and MAPK pathways. Acts synergically with IL22, TNF and IL1B in inducing antibacterial peptides. May have protective function by maintaining epithelial homeostasis after an inflammatory challenge, such as that caused in the intestine by dextran sulfate sodium in a colitis model. May also promote an inflammatory phenotype, such as skin in a psoriasis model. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases, such as autoimmune encephalitis. {ECO:0000269|PubMed:21982598, ECO:0000269|PubMed:21993848, ECO:0000269|PubMed:21993849}.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Expressed by epithelial cells after bacterial challenge. Low expression, if any, in lymphocytes. {ECO:0000269|PubMed:21993848}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Interleukin 17C (IL17C), Mouse, ELISA Kit - SED347Mu from ARP American Research Products Category ELISA Kit Prices $740.00 Sizes 96 t Sensitivity 5.8pg/mL Range 15.6-1,000pg/mL

Interleukin 17C (IL17C), Mouse, CLIA Kit - SCD347Mu from ARP American Research Products Category CLIA Kit Prices $864.00 Sizes 96 t Sensitivity 5.7pg/mL Range 15.6-1,000pg/mL

IL-17C, ELISA Kit - MBS177367 from MyBioSource Category ELISA Kit Prices $425.00 Sizes 1x96 wells Sensitivity < 10pg/ml Range 125pg/ml-8000pg/ml

Interleukin 17C, ELISA Kit - MBS069941 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0pg/ml. Range 3.12pg/ml-100pg/ml.

Mouse IL-17C PicoKine™ ELISA Kit EK0790 - EK0790 from Boster Bio Category ELISA Kit Prices $369.00 Sizes 1 kit Sensitivity <10pg/ml Range 125pg/ml-8000pg/ml *This assay range is determined using common samples. For samples with low target protein concentrations, users can adjust the standard curve to extend the lower limit of assay range.

ELISA Kit for Interleukin 17C (IL17C) - SED347Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.3pg/mL. Range 15.625-1000pg/mL The standard curve concentrations used for the ELISA's were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.625pg/mL

CLIA Kit for Interleukin 17C (IL17C) - SCD347Mu from Cloud-clone Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.63pg/mL. Range 1.372-1000pg/mL The standard curve concentrations used for the ELISA's were 1000pg/mL, 333.33pg/mL, 111.11pg/mL, 37.04pg/mL, 12.346pg/mL, 4.115pg/mL, 1.372pg/mL

Mouse Interleukin 17C (IL17C) ELISA Kit - EKU05245 from Biomatik Category ELISA Kit Prices $756.00, $3,326.00, $6,048.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 5.8 pg/mL Range 15.62-1000 pg/mL

Mouse Interleukin 17C ELISA Kit - abx154239 from Abbexa Category ELISA Kit Range 15.63 pg/ml - 1000 pg/ml

Mouse Interleukin 17C CLIA Kit - abx190496 from Abbexa Category CLIA Kit Range 1.37 pg/ml - 1000 pg/ml

Interleukin 17C (IL17C), Mouse, ELISA Kit - DL-IL17C-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 15.6-1,000 pg/mL

IL17C - KBB-488 from Nordic BioSite Sensitivity <10pg/ml Range 125pg/ml-8000pg/ml

Mouse IL-17C ELISA Kit - abx056696 from Abbexa Category ELISA Kit Sensitivity 10 pg/ml Range 125 pg/ml - 8000 pg/ml

Mouse IL-17C ELISA Kit - EA100496 from Acris Antibodies Category ELISA Kit Prices $389.00 Sizes 1 kit Range 10

IL-17C ELISA Kit (Mouse) (OKBB00438) - OKBB00438 from Aviva Systems Biology Category ELISA Kit Prices $385.00 Sizes 96 wells Sensitivity <= 10 pg/mL Range 125 pg/mL-8,000 pg/mL

Mouse IL-17C ELISA Kit - orb314952 from Biorbyt Category ELISA Kit Prices $490.00 Sizes 96 test Sensitivity 10 pg/ml Range 125 pg/ml - 8000 pg/ml

Mouse IL-17C ELISA Kit - orb196297 from Biorbyt Category ELISA Kit Prices $612.00 Sizes 96 well Sensitivity < 10pg/ml Range 125pg/ml-8000pg/ml

Mouse IL17C ELISA Kit - abx574864 from Abbexa Category ELISA Kit Sensitivity 5.8 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Mouse IL-17C ELISA Kit - CEK1697 from Cohesion Biosciences Category ELISA Kit Prices $360.00 Sizes 96 t Sensitivity 10 pg/ml Range 125 pg/ml - 8000 pg/ml

Mouse Interleukin 17C (IL17C) ELISA Kit (CLIA) - EKU72137 from Biomatik Category ELISA Kit Prices $907.20, $3,991.68, $7,257.60 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.63pg/mL Range 1.37-1000pg/mL The standard curve concentrations used for the CLIA’s were 1000pg/mL, 333.33pg/mL, 111.11pg/mL, 37.04pg/mL, 12.35pg/mL, 4.12pg/mL, 1.37pg/mL

Mouse Interleukin 17C (IL17C) CLIA Kit - EKU09552 from Biomatik Category CLIA Kit Prices $907.00, $3,992.00, $7,258.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.63 pg/mL Range 15.62-1000 pg/mL

Mouse Il17c ELISA Kit - E056306 from Biobool Category ELISA Kit Sensitivity 10 pg/ml.

IL-17C, ELISA Kit - MBS8244569 from MyBioSource Category ELISA Kit Prices $505.00 Sizes 96 tests Sensitivity 10 pg/ml.

Interleukin 17C (IL17C), ELISA Kit - MBS2089577 from MyBioSource Category ELISA Kit Prices $535.00, $820.00, $1,125.00, $4,700.00, $8,470.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 17C (IL17C), ELISA Kit - MBS452315 from MyBioSource Category ELISA Kit Prices $385.00, $505.00, $2,200.00, $4,265.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <12.2pg/mL Range 31.2-2000pg/mL

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