Il17c

Gene Symbol	Il17c
Entrez Gene	234836
Alt Symbol	IL-17C
Species	Mouse
Gene Type	protein-coding
Description	interleukin 17C
Other Description	cytokine CX2|interleukin-17C
Swissprots	A6H6F0 Q8K4C5
Accessions	CAL40893 EDL11677 EDL11678 Q8K4C5 AF458061 AAM77565 BC145853 AAI45854 NM_145834 NP_665833
Function	Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NFKB and MAPK pathways. Acts synergically with IL22, TNF and IL1B in inducing antibacterial peptides. May have protective function by maintaining epithelial homeostasis after an inflammatory challenge, such as that caused in the intestine by dextran sulfate sodium in a colitis model. May also promote an inflammatory phenotype, such as skin in a psoriasis model. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases, such as autoimmune encephalitis. {ECO:0000269|PubMed:21982598, ECO:0000269|PubMed:21993848, ECO:0000269|PubMed:21993849}.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Expressed by epithelial cells after bacterial challenge. Low expression, if any, in lymphocytes. {ECO:0000269|PubMed:21993848}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

IL-17C Antibody [Unconjugated] - AF2306 from Novus Biologicals Prices $99.00, $365.00 Sizes 25 µg, 100 µg Host Goat Clonality Polyclonal

IL-17C Antibody (311522) [Unconjugated] - MAB23061 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Rat Clonality Monoclonal Clone 311522

IL-17C Antibody (311523) - MAB2306 from Novus Biologicals Prices $99.00, $269.00 Sizes 25 µg, 100 µg Host Rat Clonality Monoclonal Clone 311523

Anti -Interleukin 17C (IL-17C) - I8439-20R3 from USBiological Life Science Host Rat Clonality Monoclonal Clone 8B28

Interleukin 17C Antibody - abx101515 from Abbexa Host Rabbit Clonality Polyclonal

Polyclonal Antibody to Interleukin 17C (IL17C) - PAD347Mu01 from Cloud-clone Host Rabbit Clonality Polyclonal

Polyclonal Antibody to Interleukin 17C (IL17C) - PAD347Mu02 from Cloud-clone Host Rabbit Clonality Polyclonal

IL-17C Antibody (311522) [Alexa Fluor (R) 750] - IC23061S from Novus Biologicals Prices $339.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone 311522

IL-17C Antibody (311522) [Alexa Fluor (R) 647] - IC23061R from Novus Biologicals Prices $339.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone 311522

IL-17C Antibody (311522) [Alexa Fluor (R) 700] - IC23061N from Novus Biologicals Prices $339.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone 311522

IL-17C Antibody (311522) [Alexa Fluor (R) 488] - IC23061G from Novus Biologicals Prices $339.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone 311522

IL-17C Antibody (311522) [Alexa Fluor (R) 405] - IC23061V from Novus Biologicals Prices $339.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone 311522

IL-17C Antibody (311522) [Alexa Fluor (R) 350] - IC23061U from Novus Biologicals Prices $339.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone 311522

IL-17C Antibody (311522) [Alexa Fluor (R) 594] - IC23061T from Novus Biologicals Prices $339.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone 311522

Anti-IL17C Antibody A00164 - A00164 from Boster Bio Prices $290.00 Sizes 1 Host Goat Clonality Polyclonal

Anti-IL-17C Antibody A00164-1 - A00164-1 from Boster Bio Prices $245.00 Sizes 1 Host Rabbit Clonality Polyclonal

Interleukin 17C (IL17C) Polyclonal Antibody - CAU23416 from Biomatik Prices $114.00, $267.00, $382.00, $611.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg Host Rabbit Clonality Polyclonal

Anti-IL17C Picoband™ antibody A00164-3 - A00164-3 from Boster Bio Prices $240.00 Sizes 1 Host Rabbit Clonality Polyclonal

IL17C Antibody (RQ4160) - RQ4160 from NSJ Bioreagent Prices $299.00 Sizes 100 µg (0.5mg/ml if reconstituted with 0.2ml sterile DI water) Host Rabbit Clonality Polyclonal

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