Il17c

Gene Symbol	Il17c
Entrez Gene	234836
Alt Symbol	IL-17C
Species	Mouse
Gene Type	protein-coding
Description	interleukin 17C
Other Description	cytokine CX2|interleukin-17C
Swissprots	A6H6F0 Q8K4C5
Accessions	CAL40893 EDL11677 EDL11678 Q8K4C5 AF458061 AAM77565 BC145853 AAI45854 NM_145834 NP_665833
Function	Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NFKB and MAPK pathways. Acts synergically with IL22, TNF and IL1B in inducing antibacterial peptides. May have protective function by maintaining epithelial homeostasis after an inflammatory challenge, such as that caused in the intestine by dextran sulfate sodium in a colitis model. May also promote an inflammatory phenotype, such as skin in a psoriasis model. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases, such as autoimmune encephalitis. {ECO:0000269|PubMed:21982598, ECO:0000269|PubMed:21993848, ECO:0000269|PubMed:21993849}.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Expressed by epithelial cells after bacterial challenge. Low expression, if any, in lymphocytes. {ECO:0000269|PubMed:21993848}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse Il17c cDNA clone(NM_145834.3) - CDFL006138 from Creative Biomart Species Mouse Accession NM_145834.3

Mouse Il17c ORF Clone(NM_145834.3) - CDCR267674 from Creative Biomart Species Mouse Accession NM_145834.3

Mouse Il17c ORF Clone(NM_145834.3) - CDCR267675 from Creative Biomart Species Mouse Accession NM_145834.3

Mouse IL17C ORF clone(NM_145834.3) - CDCL184773 from Creative Biomart Species Mouse Accession NM_145834.3

Mouse IL18 ORF clone(NM_145834.3) - CDCL184788 from Creative Biomart Species Mouse Accession NM_145834.3

Mouse IL-17C/IL17C Gene ORF cDNA clone in cloning vector - MG50072-M from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid, C-His tag - MG50072-CH from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid, C-Myc tag - MG50072-CM from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid, N-His tag - MG50072-NH from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - MG50072-ACR from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid, N-HA tag - MG50072-NY from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - MG50072-ACG from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid - MG50072-UT from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid, N-Flag tag - MG50072-NF from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid, C-HA tag - MG50072-CY from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid, C-Flag tag - MG50072-CF from Sino Biological Species Mouse

Mouse IL-17C/IL17C Gene ORF cDNA clone expression plasmid, N-Myc tag - MG50072-NM from Sino Biological Species Mouse

Mouse IL17C ORF clone(NM_145834.3) - CDCL184773 from Creative biogene Species Mouse

Mouse IL 17C Gene - orb92857 from Biorbyt Prices $264.00 Sizes 10 μg Species Mouse

Mouse Il17c cDNA Clone(NM_145834.3) - CDFL006138 from Creative biogene Species Mouse

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