CXADR

Gene Symbol	CXADR
Entrez Gene	1525
Alt Symbol	CAR, CAR4/6, HCAR
Species	Human
Gene Type	protein-coding
Description	coxsackie virus and adenovirus receptor
Other Description	46 kD coxsackievirus and adenovirus receptor (CAR) protein|CVB3-binding protein|HCVADR|coxsackievirus B-adenovirus receptor|coxsackievirus and adenovirus receptor
Swissprots	D3YHP0 B7WPI3 Q8WWT8 P78310 B2R8V8 O00694 Q8WWT6 Q8WWT7 Q9UKV4
Accessions	AAF05908 AAF24344 AAG01088 EAX10030 EAX10031 EAX10032 EAX10033 P78310 AF124598 AAD31772 AI498294 AK313526 BAG36305 AY072910 AAL68878 AY072911 AAL68879 AY072912 AAL68880 BC003684 AAH03684 BC010536 AAH10536 BM547121 BT019876 AAV38679 CV570985 DQ891181 ABM82107 DQ894363 ABM85289 GU474812 ADC84500 U90716 AAC51234 Y07593 CAA68868 XM_011529475 XP_011527777 XM_011529476 XP_011527778 XM_011529477 XP_011527779 XM_011529478 XP_011527780 XM_011529479 XP_011527781 NM_001207063 NP_001193992 NM_001207064 NP_001193993 NM_001207065 NP_001193994 NM_001207066 NP_001193995 NM_001338 NP_001329
Function	Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T- cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T- cells that in turn stimulate epithelial tissues repair. {ECO:0000269|PubMed:11734628, ECO:0000269|PubMed:12297051, ECO:0000269|PubMed:15800062, ECO:0000269|PubMed:19064666, ECO:0000269|PubMed:9096397}.
Subcellular Location	Isoform 5: Secreted.
Tissue Specificity	Expressed in pancreas, brain, heart, small intestine, testis, prostate and at a lower level in liver and lung. Isoform 5 is ubiquitously expressed. Isoform 3 is expressed in heart, lung and pancreas. In skeletal muscle, isoform 1 is found at the neuromuscular junction and isoform 2 is found in blood vessels. In cardiac muscle, isoform 1 and isoform 2 are found at intercalated disks. In heart expressed in subendothelial layers of the vessel wall but not in the luminal endothelial surface. Expression is elevated in hearts with dilated cardiomyopathy. {ECO:0000269|PubMed:10490761, ECO:0000269|PubMed:11457744, ECO:0000269|PubMed:11549277, ECO:0000269|PubMed:9096397}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CXADR ELISA Kit (Sandwich ELISA) - LS-F9609 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.054 ng/ml Range 0.156-10 ng/ml

Human CXADR ELISA Kit (Sandwich ELISA) - LS-F11247 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 0.156-10 ng/ml

Human CXADR ELISA Kit - abx151211 from Abbexa Category ELISA Kit Sensitivity 0.065 ng/ml Range 0.156 ng/ml - 10 ng/ml

Coxsackievirus and adenovirus receptor, CXADR, Human, ELISA Kit - E13929h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 78-5000 pg/mL

Coxsackie Virus and AdenoVirus Receptor - MBS707003 from MyBioSource Category ELISA Kit

Coxsackie Virus and AdenoVirus Receptor - MBS707238 from MyBioSource Category ELISA Kit

Coxsackie Virus and AdenoVirus Receptor, ELISA Kit - MBS093750 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Coxsackie Virus and AdenoVirus Receptor, ELISA Kit - MBS078672 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Coxsackie Virus and AdenoVirus Receptor, ELISA Kit - MBS094057 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Coxsackie Virus and AdenoVirus Receptor, ELISA Kit - MBS105839 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

coxsackie virus and adenovirus receptor, ELISA Kit - MBS919152 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.11 ng/ml Range 0.45 ng/ml-30 ng/ml

Coxsackie Virus and AdenoVirus Receptor, ELISA Kit - MBS059523 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Coxsackie Virus and AdenoVirus Receptor, ELISA Kit - MBS064148 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Coxsackie Virus And Adenovirus Receptor (CXADR), ELISA Kit - MBS2000196 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.054ng/mL. Range 0.156-10ng/mL

ELISA Kit for Coxsackie Virus And Adenovirus Receptor (CXADR) - SEJ305Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Coxsackievirus and adenovirus receptor(CXADR) ELISA kit - CSB-EL006237HU from Cusabio Category ELISA Kit Sensitivity 0.11 ng/ml Range 0.45 ng/ml-30 ng/ml

Bovine CXADR ELISA Kit (Custom ELISA) - LS-F17087 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse CXADR ELISA Kit (Custom ELISA) - LS-F17088 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Rat CXADR ELISA Kit (Custom ELISA) - LS-F17089 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Custom Human CXADR ELISA - ELH-CXADR from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Coxsackie Virus and AdenoVirus Receptor, ELISA Kit - MBS076206 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Coxsackie Virus And Adenovirus Receptor (CXADR) ELISA Kit - EKU03482 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.054 ng/mL Range 0.156-10 ng/mL

Human Coxsackievirus and adenovirus receptor ELISA Kit - abx250834 from Abbexa Category ELISA Kit Range 78 pg/ml - 5000 pg/ml

Custom Human CXADR Elisa kit - orb305245 from Biorbyt Category ELISA Kit Prices $1,148.00, $1,981.00, $4,284.00 Sizes 96 assays, 192 assays, 480 assays

Human CXADR ELISA Kit - orb371108 from Biorbyt Category ELISA Kit Prices $553.00, $621.00 Sizes 48 test, 96 test Range Detection Range: 0.156-10ng/mL Detection low threshold: 0.065ng/mL

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