Trpc6

Gene Symbol Trpc6
Entrez Gene 22068
Alt Symbol AV025995, LLHWJM002, LLHWJM003, LLHWJM004, TRP-6, Trrp6, mtrp6
Species Mouse
Gene Type protein-coding
Description transient receptor potential cation channel, subfamily C, member 6
Other Description calcium entry channel|short transient receptor potential channel 6|transient receptor protein 6
Swissprots Q9Z2J1 Q61143 B9EIW2
Accessions EDL24957 EDL24958 Q61143 AF057748 AAC64394 AK086446 AK133864 BAE21896 AK137447 BC067391 AAH67391 BC068310 AAH68310 BC141131 AAI41132 U49069 AAC06146 XM_006509849 XP_006509912 XM_006509850 XP_006509913 XM_011242359 XP_011240661 XM_011242360 XP_011240662 NM_001282086 NP_001269015 NM_001282087 NP_001269016 NM_013838 NP_038866
Function Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Lung and brain.
Top Pathways cGMP-PKG signaling pathway

Anti-TRPC6 (phospho S814) antibody - ab104532 from Abcam

Host Rabbit
Clonality Polyclonal
IHC image of TRPC6 staining in mouse placenta formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab104532, 1/1000 dilution, for 15 mins at room temperature. A goat anti-rabbit biotinylated secondary antibody was used to detect the primary, and visualized using an HRP conjugated ABC system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-TRPC6 antibody - ab81111 from Abcam

Prices $378.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal
ab81111 staining TRPC6 in Rat cultured cardiomyocytes by Immunocytochemistry/ Immunoflourescence. Cells were PFA-fixed and permeabilized in 0.2% Triton X-100 prior to blocking in 5% serum for 30 minutes at 25°C. The primary antibody was diluted 1/200 in IHC-TEK antibody diluent and incubated with the sample for 1 hour at 25°C. The secondary antibody was Alexa Fluor® 568-conjugated Goat anti-Rabbit polyclonal, diluted 1/200.Red - TRPC6; Green - Alpha Actinin; Blue - DAPI;See Abreview

Anti-TRPC6 antibody - ab136824 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal

TRPC6-extracellular-Antibody - AG1321 from Abgent, a WuXi AppTec company

Prices $375.00, $475.00, $575.00
Sizes 25 µl, 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of rat brain lysates: 1. Anti-TRPC6 (extracellular) antibody (#AG1321), (1:200). 2. Anti-TRPC6 (extracellular) antibody, preincubated with the control peptide antigen.

TRPC6-Antibody - AG1455 from Abgent, a WuXi AppTec company

Prices $375.00, $475.00, $575.00
Sizes 25 µl, 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of  rat brain membranes: 1. Anti-TRPC6 antibody (#AG1455), (1:200). 2. Anti-TRPC6 antibody, preincubated with the control peptide antigen.

Goat anti-Trpc6 (mouse) middle region Antibody (OAEB02953) - OAEB02953 from Aviva Systems Biology

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

TRPC6 Antibody (OAEC00657) - OAEC00657 from Aviva Systems Biology

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Trpc6 antibody - orb12355 from Biorbyt

Prices $408.00
Sizes 100 μg
Host Goat
Clonality Polyclonal

TRPC6 Antibody - abx116199 from Abbexa

Host Rabbit
Clonality Polyclonal

Anti-TRPC6 Antibody - AC21-2888 from Abcore

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (AMCA) - AC21-2888-01 from Abcore

Prices $495.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (AP) - AC21-2888-02 from Abcore

Prices $505.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (APC) - AC21-2888-03 from Abcore

Prices $515.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (APC-Cy5.5) - AC21-2888-04 from Abcore

Prices $539.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (APC-Cy7) - AC21-2888-05 from Abcore

Prices $539.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (Avidin) - AC21-2888-06 from Abcore

Prices $519.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (Biotin) - AC21-2888-07 from Abcore

Prices $519.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (BPE) - AC21-2888-08 from Abcore

Prices $499.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (Cy3) - AC21-2888-09 from Abcore

Prices $505.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (Cy5) - AC21-2888-10 from Abcore

Prices $505.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (Cy5.5) - AC21-2888-11 from Abcore

Prices $505.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (FITC) - AC21-2888-12 from Abcore

Prices $489.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (Glucose Oxidase) - AC21-2888-13 from Abcore

Prices $515.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (HRP) - AC21-2888-14 from Abcore

Prices $475.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-TRPC6 Antibody (PE-Cy5) - AC21-2888-15 from Abcore

Prices $539.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
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