Gene Symbol | SERPINF2 |
---|---|
Entrez Gene | 5345 |
Alt Symbol | A2AP, AAP, ALPHA-2-PI, API, PLI |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
Other Description | alpha-2-AP|alpha-2-antiplasmin|alpha-2-plasmin inhibitor|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2|serpin F2 |
Swissprots | Q9UCG2 Q8N5U7 B4E1B7 P08697 Q9UCG3 |
Accessions | AAA51554 AAA51555 EAW90578 EAW90579 EAW90580 EAW90581 P08697 AK303763 BAG64729 AL564784 BC031592 AAH31592 BX107460 CK300825 D00116 BAA00070 D00174 BAA00124 DQ890796 ABM81722 DQ893951 ABM84877 J02654 AAA35543 XM_005256699 XP_005256756 XM_005256700 XP_005256757 XM_005256701 XP_005256758 XM_005256703 XP_005256760 XM_011546754 XP_011545056 XM_011546755 XP_011545057 XM_011546756 XP_011545058 NM_000934 NP_000925 NM_001165920 NP_001159392 NM_001165921 NP_001159393 |
Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. {ECO:0000269|PubMed:15853774}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Top Pathways | Complement and coagulation cascades |
α-2 antiplasmin CRISPR/Cas9 KO Plasmid (h) - sc-403792 from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin HDR Plasmid (h) - sc-403792-HDR from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin Double Nickase Plasmid (h) - sc-403792-NIC from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin Double Nickase Plasmid (h2) - sc-403792-NIC-2 from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin CRISPR Activation Plasmid (h) - sc-403792-ACT from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin CRISPR Activation Plasmid (h2) - sc-403792-ACT-2 from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin Lentiviral Activation Particles (h) - sc-403792-LAC from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin Lentiviral Activation Particles (h2) - sc-403792-LAC-2 from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin siRNA (h) - sc-61924 from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin shRNA Plasmid (h) - sc-61924-SH from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin shRNA (h) Lentiviral Particles - sc-61924-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU136461 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN1844 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1844 from Sigma-Aldrich
|
||||||||
SERPINF2 siRNA (Human) - CRH3584 from Cohesion Biosciences
|
||||||||
SERPINF2 - MBS8232231 from MyBioSource
|
||||||||
shRNA set against Human SERPINF2 (NM_000934.3) - SHH405396 from Creative biogene
|
||||||||
shRNA set against Human SERPINF2(NM_000934.3) - SHR218148 from Creative biogene
|
||||||||
α-2 antiplasmin CRISPR/Cas9 KO Plasmid (h2) - sc-403792-KO-2 from Santa Cruz Biotechnology
|
||||||||
α-2 antiplasmin HDR Plasmid (h2) - sc-403792-HDR-2 from Santa Cruz Biotechnology
|
||||||||
Human SERPINF2 siRNA - orb264086 from Biorbyt
|
||||||||
SERPINF2 shRNA Plasmid (Human) - CHH3584 from Cohesion Biosciences
|
||||||||
SERPINF2 miRNA 3'UTR clone - MiUTR1H-09305 from Creative biogene
|
||||||||
SERPINF2 miRNA 3'UTR clone - MiUTR3H-12766 from Creative biogene
|
||||||||
SERPINF2 miRNA 3'UTR clone - MiUTR3H-12767 from Creative biogene
|