Gene Symbol | SERPINF2 |
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Entrez Gene | 5345 |
Alt Symbol | A2AP, AAP, ALPHA-2-PI, API, PLI |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
Other Description | alpha-2-AP|alpha-2-antiplasmin|alpha-2-plasmin inhibitor|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2|serpin F2 |
Swissprots | Q9UCG2 Q8N5U7 B4E1B7 P08697 Q9UCG3 |
Accessions | AAA51554 AAA51555 EAW90578 EAW90579 EAW90580 EAW90581 P08697 AK303763 BAG64729 AL564784 BC031592 AAH31592 BX107460 CK300825 D00116 BAA00070 D00174 BAA00124 DQ890796 ABM81722 DQ893951 ABM84877 J02654 AAA35543 XM_005256699 XP_005256756 XM_005256700 XP_005256757 XM_005256701 XP_005256758 XM_005256703 XP_005256760 XM_011546754 XP_011545056 XM_011546755 XP_011545057 XM_011546756 XP_011545058 NM_000934 NP_000925 NM_001165920 NP_001159392 NM_001165921 NP_001159393 |
Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. {ECO:0000269|PubMed:15853774}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Top Pathways | Complement and coagulation cascades |
α-2 antiplasmin (H-275) - sc-292693 from Santa Cruz Biotechnology
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α-2 antiplasmin (C-16) - sc-67506 from Santa Cruz Biotechnology
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α-2 antiplasmin (N-20) - sc-67510 from Santa Cruz Biotechnology
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α-2 antiplasmin (P-19) - sc-67511 from Santa Cruz Biotechnology
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α-2 antiplasmin (JJ-16) - sc-73658 from Santa Cruz Biotechnology
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α-2 antiplasmin (SJ-19) - sc-73659 from Santa Cruz Biotechnology
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Anti-Alpha 2 Antiplasmin antibody - ab62770 from Abcam
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Anti-Alpha 2 Antiplasmin antibody - ab198900 from Abcam
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Anti-Alpha 2 Antiplasmin antibody - ab106821 from Abcam
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Anti-Alpha 2 Antiplasmin antibody - ab48591 from Abcam
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Anti-Alpha 2 Antiplasmin antibody - ab88296 from Abcam
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Anti-Alpha 2 Antiplasmin antibody - ab96626 from Abcam
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Anti-Alpha 2 Antiplasmin antibody - ab182936 from Abcam
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Anti-Alpha 2 Antiplasmin antibody [710-1E-94] - ab30994 from Abcam
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Anti-Alpha 2 Antiplasmin antibody [EPSIS17] - ab150414 from Abcam
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Anti-SERPINF2 / Alpha-2-Antiplasmin Antibody (aa454-468) IHC-plus⢠- LS-B2768 from LifeSpan Bioscience
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Anti-SERPINF2 / Alpha-2-Antiplasmin Antibody (aa188-453) IHC-plus⢠- LS-B10788 from LifeSpan Bioscience
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Anti-SERPINF2 / Alpha-2-Antiplasmin Antibody - LS-C20653 from LifeSpan Bioscience
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Anti-SERPINF2 / Alpha-2-Antiplasmin Antibody - LS-C20654 from LifeSpan Bioscience
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Anti-SERPINF2 / Alpha-2-Antiplasmin Antibody - LS-C20656 from LifeSpan Bioscience
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Anti-SERPINF2 / Alpha-2-Antiplasmin Antibody (HRP) - LS-C20657 from LifeSpan Bioscience
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Anti-SERPINF2 / Alpha-2-Antiplasmin Antibody - LS-C20658 from LifeSpan Bioscience
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Anti-SERPINF2 / Alpha-2-Antiplasmin Antibody - LS-C20659 from LifeSpan Bioscience
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Anti-SERPINF2 / Alpha-2-Antiplasmin Antibody - LS-C20660 from LifeSpan Bioscience
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Anti-SERPINF2 / Alpha-2-Antiplasmin Antibody - LS-C20661 from LifeSpan Bioscience
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