Gene Symbol | SERPINF2 |
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Entrez Gene | 5345 |
Alt Symbol | A2AP, AAP, ALPHA-2-PI, API, PLI |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
Other Description | alpha-2-AP|alpha-2-antiplasmin|alpha-2-plasmin inhibitor|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2|serpin F2 |
Swissprots | Q9UCG2 Q8N5U7 B4E1B7 P08697 Q9UCG3 |
Accessions | AAA51554 AAA51555 EAW90578 EAW90579 EAW90580 EAW90581 P08697 AK303763 BAG64729 AL564784 BC031592 AAH31592 BX107460 CK300825 D00116 BAA00070 D00174 BAA00124 DQ890796 ABM81722 DQ893951 ABM84877 J02654 AAA35543 XM_005256699 XP_005256756 XM_005256700 XP_005256757 XM_005256701 XP_005256758 XM_005256703 XP_005256760 XM_011546754 XP_011545056 XM_011546755 XP_011545057 XM_011546756 XP_011545058 NM_000934 NP_000925 NM_001165920 NP_001159392 NM_001165921 NP_001159393 |
Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. {ECO:0000269|PubMed:15853774}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Top Pathways | Complement and coagulation cascades |
Active human Alpha 2 Antiplasmin full length protein - ab77936 from Abcam
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Human Alpha 2 Antiplasmin full length protein - ab152615 from Abcam
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Human Alpha 2 Antiplasmin full length protein - ab167800 from Abcam
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Human Alpha 2 Antiplasmin full length protein - ab90921 from Abcam
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Human Alpha 2 Antiplasmin full length protein - ab81750 from Abcam
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Mouse Alpha 2 Antiplasmin full length protein - ab93268 from Abcam
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Mouse Alpha 2 Antiplasmin full length protein - ab93269 from Abcam
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SERPINF2 / Alpha-2-Antiplasmin Antibody Blocking Peptide - LS-E21649 from LifeSpan Bioscience
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SERPINF2 / Alpha-2-Antiplasmin Antibody Blocking Peptide - LS-E26806 from LifeSpan Bioscience
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Recombinant Human Serpin F2/alpha 2-Antiplasmin Protein - H00005345-P01 from Novus Biologicals
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Alpha2-antiplasmin blocking peptide - GTX88657-PEP from GeneTex
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Recombinant Human Serpin F2/alpha 2-Antiplasmin, CF - 1470-PI-010 from R&D Systems
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Human Alpha 2 Antiplasmin Protein (OPMA04240) - OPMA04240 from Aviva Systems Biology
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Human Alpha 2 Antiplasmin protein - orb82118 from Biorbyt
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Human A2AP protein - orb83631 from Biorbyt
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alpha 2 Antiplasmin protein - 30C-CP3004 from Fitzgerald
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SERPINF2 Blocking Peptide - 33R-1815 from Fitzgerald
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Human a2PI Protein - abx065260 from Abbexa
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alpha 2 Antiplasmin Peptide - AC21-1639-P from Abcore
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Alpha-2-antiplasmin / SERPINF2 - BA673 from Acris Antibodies
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Alpha-2-antiplasmin / SERPINF2 - H00005345-P01-10 from Acris Antibodies
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Alpha-2-antiplasmin / SERPINF2 - H00005345-P01-25 from Acris Antibodies
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Human Alpha 2 Antiplasmin - MD-14-0005P from RayBiotech
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Alpha-2-Plasmin Inhibitor (a2PI), Human - 20-6377 from ARP American Research Products
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Alpha2-antiplasmin Peptide - 45-243P from ProSci
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