ARAP2

Gene Symbol ARAP2
Entrez Gene 116984
Alt Symbol CENTD1, PARX
Species Human
Gene Type protein-coding
Description ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Other Description Arf and Rho GAP adapter protein 2|arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2|centaurin, delta 1|centaurin-delta-1|cnt-d1
Swissprots Q96P49 Q96L70 Q9Y4E4 Q7Z2L5 Q4W5D2 Q8WZ64
Accessions AAY40927 EAW92870 EAW92871 EAW92872 Q8WZ64 AB011152 BAA25506 AF411982 AAL04166 AF439781 AAL32459 AK126864 AW274408 AY049733 AAL12170 BC105089 AAI05090 BC105091 AAI05092 BC150258 AAI50259 BC160097 AAI60097 BX104334 XM_005262642 XP_005262699 NM_015230 NP_056045 NM_139182
Function Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Detected in brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:11804590}.
Top Pathways Endocytosis

ARAP2 (C-13) - sc-51026 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ARAP2 (G-15) - sc-51027 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ARAP2 (H-157) - sc-292718 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ARAP2 (L-17) - sc-51028 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ARAP2 (S-13) - sc-51031 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CENTD1 antibody - ab130540 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CENTD1 antibody (ab130540) at 1/100 dilution + NCI-H292 cell line lysates at 35 µg

Anti-CENTD1 antibody - ab85794 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-CENTD1 antibody (ab85794) at 2 µg/mlLane 1 : human kidney lysate without immunising peptideLane 2 : human kidney lysate with immunising peptide

Anti-ARAP2 / CENTD1 Antibody (aa78-93) - LS-C143727 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ARAP2 / CENTD1 Antibody (aa1670-1720) - LS-C143786 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARAP2 / CENTD1 Antibody (aa78-93) - LS-C148558 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ARAP2 / CENTD1 Antibody (aa63-93, AP) - LS-C252871 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARAP2 / CENTD1 Antibody (aa63-93, APC) - LS-C252872 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARAP2 / CENTD1 Antibody (aa63-93, Biotin) - LS-C252873 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARAP2 / CENTD1 Antibody (aa63-93, FITC) - LS-C252874 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARAP2 / CENTD1 Antibody (aa1670-1720) - LS-C148546 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of ARAP2 in human kidney lysate in the 1) absence and 2) presence of immunizing peptide using LS-C148546 at 1.0 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.

Anti-ARAP2 / CENTD1 Antibody (aa63-93, Azide-free, HRP) - LS-C252875 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARAP2 / CENTD1 Antibody (aa63-93, PE) - LS-C252876 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARAP2 / CENTD1 Antibody (aa63-93) - LS-C156448 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ARAP2 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The ARAP2 antibody detected the ARAP2 protein (arrow).

Anti-ARAP2 / CENTD1 Antibody (aa62-93) - LS-C319556 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARAP2 / CENTD1 Antibody (aa250-300) - LS-C289123 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CENTD1 by Western Blot. Samples: Whole cell lysate (5, 15 and 50 ug) from HeLa cells. Antibodies: Affinity purified rabbit anti-CENTD1 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

CENTD1 Antibody - NBP2-24620 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

CENTD1 Antibody - NBP2-23697 from Novus Biologicals

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CENTD1 Antibody - NBP1-84542 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-ARAP2 (N-TERM) antibody produced in rabbit - SAB1304254 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ARAP2 (N-term): <B>Cat. No. SAB1304254</B>: ARAP2 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35 μg/lane).

Anti-ARAP2 antibody produced in rabbit - HPA035925 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ARAP2: <B>Cat. No. HPA035925</B>: Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in bone marrow poietic cells.
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