IL33

Gene Symbol IL33
Entrez Gene 403810
Alt Symbol DVS27
Species Dog
Gene Type protein-coding
Description interleukin 33
Other Description IL-33|interleukin-33
Swissprots O97863
Accessions O97863 AB024517 BAA75891 XM_005626370 XP_005626427 NM_001003180 NP_001003180
Function Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10566975}. Chromosome {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Secreted {ECO:0000250}. Note=Associates with heterochromatin and mitotic chromosomes. Translocation from the nucleus occurs upon biomechanical strain, depends on an intact microtubule network, and is ATP-dependent (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in cultured umbilical artery smooth muscle cells after stimulation with IL1A and IL1B, and to a lesser extent with IFNG. Expressed in vasospastic cerebral arteries after subarachnoid hemorrhage. {ECO:0000269|PubMed:10566975}.
Top Pathways Cytosolic DNA-sensing pathway, Influenza A

Interleukin 33, Canine, ELISA Kit - E08I0204 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 1.0pg/ml
Range 50-1000pg/ml?

Interleukin-33 (IL33), Dog, ELISA Kit - CSB-EL011656DO from ARP American Research Products

Category ELISA Kit
Prices $550.00, $790.00, $791.00, $794.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Interleukin-33, IL33, Dog, ELISA Kit - E1980d from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t

Canine IL-33 ELISA Kit - CI0211 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Canine IL-33 ELISA Kit - CI0312 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Dog Interleukin-33(IL33) ELISA kit - CSB-EL011656DO from Cusabio

Category ELISA Kit
Sensitivity 5.86 pg/ml
Range 23.44 pg/ml-1500 pg/ml

Canine Interleukin 33 ELISA - E08I0204 from BlueGene Biotech

Category ELISA Kit

interleukin 33, ELISA Kit - MBS936399 from MyBioSource

Category ELISA Kit
Prices $550.00, $795.00, $2,890.00, $5,465.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 5.86 pg/ml
Range 23.44 pg/ml-1500 pg/ml

Dog Interleukin-33 (IL33) ELISA Kit - EKC32082 from Biomatik

Category ELISA Kit
Prices $795.00, $3,021.00, $5,645.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 5.86 pg/ml
Range 23.44 pg/ml-1500 pg/ml

Canine IL33 ELISA Kit - E086611 from Biobool

Category ELISA Kit

Canine IL-33 ELISA Kit - ECI0312 from ABclonal

Category ELISA Kit
Prices $495.00
Sizes 96 t

Canine IL-33 ELISA Kit - ECI0211 from ABclonal

Category ELISA Kit
Prices $495.00
Sizes 96 t

Interleukin-33, ELISA Kit - MBS2887057 from MyBioSource

Category ELISA Kit
Prices $380.00, $500.00, $2,170.00, $3,840.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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