Il1r1

Gene Symbol	Il1r1
Entrez Gene	16177
Alt Symbol	CD121a, CD121b, IL-1R1, IL-iR, Il1r-1
Species	Mouse
Gene Type	protein-coding
Description	interleukin 1 receptor, type I
Other Description	CD121 antigen-like family member A|IL-1 receptor alpha chain|IL-1R-1|IL-1R-alpha|IL-1RT-1|IL-1RT1|interleukin-1 receptor alpha|interleukin-1 receptor type 1|interleukin-1 receptor type I|p80
Swissprots	P13504
Accessions	EDL14572 P13504 AK048550 BAC33372 AK054137 BAC35666 AK166301 BC109135 AAI09136 M20658 AAA39279 XM_006495713 XP_006495776 XM_006495714 XP_006495777 XM_006495715 XP_006495778 XM_006495716 XP_006495779 XM_006495717 XP_006495780 XM_006495718 XP_006495781 XM_006495719 XP_006495782 XM_006495720 XP_006495783 XM_006495721 XP_006495784 XM_006495722 XP_006495785 XM_006495723 XP_006495786 XM_011238436 XP_011236738 NM_001123382 NP_001116854 NM_008362 NP_032388
Function	Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass type I membrane protein. Cell membrane {ECO:0000305}. Secreted {ECO:0000250}.
Top Pathways	Amoebiasis, Inflammatory mediator regulation of TRP channels, HTLV-I infection, Osteoclast differentiation, Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Recombinant Mouse IL-1 RI Fc Chimera, CF - 771-MR-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Mouse IL1R1 protein - orb139156 from Biorbyt Category Protein Prices $323.00, $527.00 Sizes 50 μg, 100 μg Source Human Cells Species Mouse

Mouse IL1R1 Protein - abx067421 from Abbexa Category Protein Source E.coli Species Mouse

Recombinant Mouse Il1r1, His tagged - Il1r1-5188M from Creative Biomart Category Protein Source Human Cells Species Mouse

Recombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged - Il1r1-5651M from Creative Biomart Category Protein Source Spodopterafrugiperda, Sf 21 (baculovirus)-derived.

Recombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged - Il1r1-5653M from Creative Biomart Category Protein Source Murine myeloma cellline, NS0-derived.

Recombinant Mouse Interleukin 1 Receptor, Type I - Il1r1-1753M from Creative Biomart Category Protein Source NSO Cells.

Mouse IL-1 receptor 1 Recombinant (CD121a) - RKP13504 from Reprokine Category Protein Prices $160.00, $480.00, $1,950.00 Sizes 20 µg, 100 µg, 500 µg Source Optimized DNA sequence encoding Human extracellular domain of mouse IL-1 receptor type 1 including a C-terminal His tag was expressed in HEK293 cells. Species Mouse

Mouse IL1R1 / CD121a Protein (His Tag) - 50807-M08H-50 from Sino Biological Category Protein Prices $178.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Mouse

Mouse IL1R1 / CD121a Protein (Fc Tag) - 50807-M02H-50 from Sino Biological Category Protein Prices $138.00, $248.00 Sizes 50 µg, 100 µg Source Human Cells Species Mouse

Recombinant Interleukin 1 Receptor Type I (IL1R1) - RPA066Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Interleukin 1 Receptor Type I (IL1R1) - RPA066Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Interleukin-1 receptor type 1(Il1r1) - CSB-YP011621MO CSB-EP011621MO CSB-BP011621MO CSB-MP011621MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse IL-1 RI Fc Chimera Protein, CF - 771-MR from R&D Systems Category Protein Prices $419.00 Sizes 100 µg Source Mouse myeloma cell line, NS0-derived Mouse IL-1 RI (Leu20 - Lys338) Accession # P13504 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus Species Mouse

Recombinant Mouse IL1R1 / CD121a Protein (His tag) - PKSM040477 from Elabscience Category Protein Source Human Cells Species Mouse

Recombinant Mouse IL1R1 / CD121a Protein (Fc tag) - PKSM040478 from Elabscience Category Protein Source Human Cell Species Mouse

Mouse IL1 Receptor protein - orb371811 from Biorbyt Category Protein Prices $196.00, $366.00, $944.00, $1,454.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Mouse

IL1R1 Recombinant Protein (OPCD04347) - OPCD04347 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Mouse IL1R1 / CD121a Protein (Fc Tag) - 50807-M02H from ABclonal Category Protein Prices $138.00, $248.00 Sizes 50 µg, 100 µg Source Human Cells Species Mouse

Mouse IL1R1 / CD121a Protein (His Tag) - 50807-M08H from ABclonal Category Protein Prices $178.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Mouse

IL-1 receptor 1 (CD121a) , Recombinant Protein - MBS553288 from MyBioSource Category Protein Prices $220.00, $540.00, $1,915.00 Sizes 20 µg, 100 µg, 500 µg Source HEk293 Cells

IL1R1 / CD121a, Recombinant Protein - MBS2546780 from MyBioSource Category Protein Prices $475.00, $775.00 Sizes 50 µg, 100 µg Source Human Cells

IL1R1 / CD121a, Recombinant Protein - MBS2546781 from MyBioSource Category Protein Prices $375.00, $650.00 Sizes 50 µg, 100 µg Source Human Cells

Interleukin-1 receptor type 1, Recombinant Protein - MBS7042901 from MyBioSource Category Protein Prices $1,355.00, $2,340.00, $3,545.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Mouse

Interleukin-1 receptor type 1 (Il1r1), Recombinant Protein - MBS956542 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

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