Name | Recombinant Mouse IL-1 RI Fc Chimera Protein, CF |
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Supplier | R&D Systems |
Catalog | 771-MR |
Category | Protein |
Prices | $419.00 |
Sizes | 100 µg |
Species Reactivities | Mouse |
Nature | Recombinant |
Source | Mouse myeloma cell line, NS0-derived Mouse IL-1 RI (Leu20 - Lys338) Accession # P13504 IEGRMD Human IgG 1 (Pro100 - Lys330) N-terminus C-terminus |
Purity | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain |
Bioactivity | Measured by its ability to inhibit IL-1 alpha -dependent proliferation in D10.G4.1 mouse helper T cells. Symons, J.A. et al . (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 272. Approximately 0.005‑0.015 µg/mL of IL-1 sRI/Fc Chimera will inhibit 50% of the biological response due to 50 pg/mL of rmIL-1a. |
Endotoxin | <0.10 EU per 1 μg of the protein by the LAL method. |
SwissProt/Accession | P13504 |
Gene | Il1r1 |
Sequence | Leu20 |
Supplier Page | Shop |
Grayson BE, Levasseur PR, Williams SM, Smith MS, Marks DL, Grove KL. Endocrinology. 2010 Apr;151(4):1622-32.
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