EIF3F

Gene Symbol EIF3F
Entrez Gene 8665
Alt Symbol EIF3S5, eIF3-p47
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 3, subunit F
Other Description deubiquitinating enzyme eIF3f|eIF-3-epsilon|eIF3-epsilon|eukaryotic translation initiation factor 3 subunit F|eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD)|eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa
Swissprots A8K0S2 Q6IB45 Q8N978 O00303
Accessions EAW68637 O00303 AK027739 AK093511 BAG52733 AK095574 BAC04577 AK289637 BAF82326 AK291354 BAF84043 AK293826 BAG57230 AK297621 BAG59997 BC000490 AAH00490 BC073753 BT006894 AAP35540 CB141463 CD050033 CR456959 CAG33240 DQ890766 ABM81692 HQ448263 ADQ32743 U94855 AAD03467 NM_003754 NP_003745
Function Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. {ECO:0000255|HAMAP- Rule:MF_03005, ECO:0000269|PubMed:21124883}.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03005}.
Top Pathways RNA transport

eIF3ε siRNA (h) - sc-105324 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eIF3ε shRNA Plasmid (h) - sc-105324-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eIF3ε shRNA (h) Lentiviral Particles - sc-105324-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EIF3F RNAi - H00008665-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU012901 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7762 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7762 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00074 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00074

EIF3F siRNA (Human) - CRH5700 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EIF3F - MBS8229178 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EIF3F (NM_003754.2) - SHH284485 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human EIF3S5(NM_003754.2) - SHH029279 from Creative biogene

Category siRNA
Species Reactivities Human

Human EIF3F siRNA - orb266202 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EIF3F shRNA Plasmid (Human) - CHH5700 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EIF3F miRNA 3'UTR clone - MiUTR1H-03167 from Creative biogene

Species Reactivities Human
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