PPP6C

Gene Symbol	PPP6C
Entrez Gene	5537
Alt Symbol	PP6, PP6C
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 6, catalytic subunit
Other Description	serine/threonine protein phosphatase catalytic subunit|serine/threonine-protein phosphatase 6 catalytic subunit
Swissprots	B7Z5K9 Q9UIC9 B2R5V6 Q5U0A2 O00743 B7Z2W9
Accessions	EAW87611 EAW87612 EAW87613 O00743 AA251321 AF035158 AAD45400 AK295190 BAH12005 AK295752 BAH12178 AK299087 BAH12945 AK312332 BAG35253 AK316527 BAH14898 BC006990 AAH06990 BT019708 AAV38514 CB250498 DB037210 DC307002 DC334216 DC369815 X92972 CAA63549 XM_011518847 XP_011517149 NM_001123355 NP_001116827 NM_001123369 NP_001116841 NM_002721 NP_002712
Function	Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. {ECO:0000269|PubMed:10227379, ECO:0000269|PubMed:17079228, ECO:0000269|PubMed:17568194, ECO:0000269|PubMed:9013334}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:16769727, ECO:0000269|PubMed:17568194}.
Tissue Specificity	Ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen. {ECO:0000269|PubMed:16769727, ECO:0000269|PubMed:9013334}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PPP6C full length protein - ab116916 from Abcam Category Protein Source Wheat germ Species Human

PPP6C Antibody Blocking Peptide - LS-E3388 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PPP6C Protein - H00005537-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PPP6C Peptide - P3331 from Novus Biologicals Category Peptide Species Human

PPP6C-Antibody-C-term-Blocking-Peptide - BP14562b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PPP6C-Antibody-N-term-Blocking-Peptide - BP8477a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PPP6C Protein - GTX108968-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

PPP6C - H00005537-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PPP6C - H00005537-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PPP6C fusion protein - Ag8554 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

PPP6C fusion protein - ag8670 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human PPP6C - PPP6C-29541TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human PPP6C, His-tagged - PPP6C-1928H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Serine/threonine-protein phosphatase 6 catalytic subunit(PPP6C - CSB-YP018583HU CSB-EP018583HU CSB-BP018583HU CSB-MP018583HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PPP6C Recombinant Protein Antigen - NBP2-13804PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PPP6C-Antibody-C-term-Blocking-Peptide - BP8477b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PPP6C Peptide, Human - M34GP12295H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein Phosphatase 6, Recombinant Protein - MBS2034601 from MyBioSource Category Protein Prices $160.00, $320.00, $495.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli Source: Prokaryotic expression Species Human

Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C), Recombinant Protein - MBS1262462 from MyBioSource Category Protein Prices $710.00, $840.00, $955.00, $980.00, $1,050.00, $1,125.00, $1,220.00, $1,235.00, $1,275.00, $1,485.00, $1,780.00, $1,850.00, $1,935.00, $2,370.00 Sizes 50 µg (E-Coli), 50 µg (Yeast), 200 µg (E-Coli), 50 µg (Baculovirus), 500 µg (E-Coli), 200 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 500 µg (Yeast), 1 mg (E-Coli), 500 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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