PPP6C

Gene Symbol	PPP6C
Entrez Gene	5537
Alt Symbol	PP6, PP6C
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 6, catalytic subunit
Other Description	serine/threonine protein phosphatase catalytic subunit|serine/threonine-protein phosphatase 6 catalytic subunit
Swissprots	B7Z5K9 Q9UIC9 B2R5V6 Q5U0A2 O00743 B7Z2W9
Accessions	EAW87611 EAW87612 EAW87613 O00743 AA251321 AF035158 AAD45400 AK295190 BAH12005 AK295752 BAH12178 AK299087 BAH12945 AK312332 BAG35253 AK316527 BAH14898 BC006990 AAH06990 BT019708 AAV38514 CB250498 DB037210 DC307002 DC334216 DC369815 X92972 CAA63549 XM_011518847 XP_011517149 NM_001123355 NP_001116827 NM_001123369 NP_001116841 NM_002721 NP_002712
Function	Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7. {ECO:0000269|PubMed:10227379, ECO:0000269|PubMed:17079228, ECO:0000269|PubMed:17568194, ECO:0000269|PubMed:9013334}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:16769727, ECO:0000269|PubMed:17568194}.
Tissue Specificity	Ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen. {ECO:0000269|PubMed:16769727, ECO:0000269|PubMed:9013334}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PP6 (C-18) - sc-69310 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

PP6 (E-2) - sc-393294 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

PP6 (H-40) - sc-367897 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

PP6 (N-16) - sc-69312 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

PP6 (S-22) - sc-130849 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

Anti-PPP6C antibody - ab16474 from Abcam Prices $370.00 Sizes 100 µl Host Sheep Clonality Polyclonal

Anti-PPP6C antibody - ab60249 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PPP6C antibody - ab154679 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C antibody [EPR8764] - ab131335 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR8764

Anti-PPP6C Antibody - LS-C26548 from LifeSpan Bioscience Prices $330.00 Sizes 100 µg Host Sheep Clonality Polyclonal

Anti-PPP6C Antibody (C-Terminus) - LS-C91601 from LifeSpan Bioscience Prices $545.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (aa90-139) - LS-C146227 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (aa264-293, AP) - LS-C266988 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody - LS-C136896 from LifeSpan Bioscience Prices $255.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (aa264-293, APC) - LS-C266989 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (aa264-293, Biotin) - LS-C266991 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (N-Terminus, APC) - LS-C281528 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (N-Terminus, AP) - LS-C281529 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (N-Terminus, Biotin) - LS-C281530 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (N-Terminus, Azide-free, HRP) - LS-C281531 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (N-Terminus, FITC) - LS-C281532 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (C-Terminus, clone EPR8764) - LS-C154572 from LifeSpan Bioscience Prices $485.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR8764

Anti-PPP6C Antibody (N-Terminus, PE) - LS-C281535 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PPP6C Antibody (clone 1B7) - LS-C197977 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1B7

Anti-PPP6C Antibody (aa264-293) - LS-C162098 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

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