Gene Symbol | C1QL3 |
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Entrez Gene | 389941 |
Alt Symbol | C1QTNF13, C1ql, CTRP13, K100 |
Species | Human |
Gene Type | protein-coding |
Description | complement component 1, q subcomponent-like 3 |
Other Description | C1q and tumor necrosis factor-related protein 13|C1q/TNF-related protein 13|complement C1q-like protein 3 |
Swissprots | Q5VWW1 A0PJY5 A0PJY4 |
Accessions | CAI58841 EAW86225 Q5VWW1 AK094686 BC127716 AAI27717 BC127717 AAI27718 BC160038 AAI60038 NM_001010908 NP_001010908 |
Function | May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Highly expressed in adipose tissue, with expression levels at least 2 orders of magnitude higher than in other tissues, including brain and kidney. {ECO:0000269|PubMed:21378161}. |
C1QL3 Antibody Blocking Peptide - LS-E803 from LifeSpan Bioscience
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C1QL3-Antibody-N-term-Blocking-peptide - BP11158a from Abgent, a WuXi AppTec company
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C1QL3 Blocking Peptide - abx161032 from Abbexa
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C1QL3 Blocking Peptide - CBP3531 from Cohesion Biosciences
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CTRP13 (globular domain) - pro10236 from Covalab
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Recombinant Human Complement C1q-like protein 3(C1QL3) - CSB-YP713354HU CSB-EP713354HU CSB-BP713354HU CSB-MP713354HU from Cusabio
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Complement component 1, q subcomponent-like 3 (C1QL3) - TP323500 from Acris Antibodies
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Recombinant Human C1qL3 Protein, CF - 9115-TN from R&D Systems
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Complement C1q-like protein 3 (C1QL3), Recombinant Protein - MBS1401654 from MyBioSource
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