Aif1

Gene Symbol Aif1
Entrez Gene 11629
Alt Symbol AI607846, AIF-1, D17H6S50E, G1, Iba1
Species Mouse
Gene Type protein-coding
Description allograft inflammatory factor 1
Other Description ionized calcium binding adapter molecule 1|ionized calcium-binding adapter molecule 1|testis specific
Swissprots O70200
Accessions AAC24189 AAC82481 BAB20757 BAB20758 CAD91187 EDL26636 EDL26637 O70200 AB013745 BAA28216 AF074959 AAC25604 AK006184 BAB24445 AK006562 BAB24654 BC021539 AAH21539 CT010265 CAJ18473 CT010385 CAJ18592 D86382 BAA86387 EF101555 ABK96804 XM_006523503 XP_006523566 XM_006523504 XP_006523567 XM_006525277 XP_006525340 XM_006525278 XP_006525341 XM_006536502 XP_006536565 XM_006536503 XP_006536566 XM_006537235 XP_006537298 XM_006537236 XP_006537299 NM_019467 NP_062340
Function Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. {ECO:0000269|PubMed:10934045, ECO:0000269|PubMed:11500035, ECO:0000269|PubMed:11722645, ECO:0000269|PubMed:11916959, ECO:0000269|PubMed:14756805}.
Subcellular Location Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Tissue Specificity Abundantly expressed in the testis, moderately in the spleen and lymph nodes and at low levels in the liver and thymus. Detected in macrophages. {ECO:0000269|PubMed:11722645}.

Iba1 CRISPR/Cas9 KO Plasmid (m) - sc-419058 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Iba1 HDR Plasmid (m) - sc-419058-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Iba1 Double Nickase Plasmid (m) - sc-419058-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Iba1 Double Nickase Plasmid (m2) - sc-419058-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Iba1 CRISPR Activation Plasmid (m) - sc-419058-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Iba1 CRISPR Activation Plasmid (m2) - sc-419058-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Iba1 Lentiviral Activation Particles (m) - sc-419058-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Iba1 Lentiviral Activation Particles (m2) - sc-419058-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Iba1 siRNA (m) - sc-62484 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Iba1 shRNA Plasmid (m) - sc-62484-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Iba1 shRNA (m) Lentiviral Particles - sc-62484-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN26469 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26469 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AIF1 siRNA (Mouse) - CRM0117 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

AIF1 - MBS8224602 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse AIF1 (NM_019467.2) - SHH233898 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Aif1(NM_019467.2) - SHG048001 from Creative biogene

Category siRNA
Species Reactivities Mouse

Iba1 CRISPR/Cas9 KO Plasmid (m2) - sc-419058-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Iba1 HDR Plasmid (m2) - sc-419058-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Mouse AIF1 siRNA - orb279593 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

AIF1 shRNA Plasmid (Mouse) - CHM0117 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

AIF1 miRNA 3'UTR clone - MiUTR1M-01342 from Creative biogene

Species Reactivities Mouse
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