Gene Symbol | Aif1 |
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Entrez Gene | 11629 |
Alt Symbol | AI607846, AIF-1, D17H6S50E, G1, Iba1 |
Species | Mouse |
Gene Type | protein-coding |
Description | allograft inflammatory factor 1 |
Other Description | ionized calcium binding adapter molecule 1|ionized calcium-binding adapter molecule 1|testis specific |
Swissprots | O70200 |
Accessions | AAC24189 AAC82481 BAB20757 BAB20758 CAD91187 EDL26636 EDL26637 O70200 AB013745 BAA28216 AF074959 AAC25604 AK006184 BAB24445 AK006562 BAB24654 BC021539 AAH21539 CT010265 CAJ18473 CT010385 CAJ18592 D86382 BAA86387 EF101555 ABK96804 XM_006523503 XP_006523566 XM_006523504 XP_006523567 XM_006525277 XP_006525340 XM_006525278 XP_006525341 XM_006536502 XP_006536565 XM_006536503 XP_006536566 XM_006537235 XP_006537298 XM_006537236 XP_006537299 NM_019467 NP_062340 |
Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. {ECO:0000269|PubMed:10934045, ECO:0000269|PubMed:11500035, ECO:0000269|PubMed:11722645, ECO:0000269|PubMed:11916959, ECO:0000269|PubMed:14756805}. |
Subcellular Location | Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. |
Tissue Specificity | Abundantly expressed in the testis, moderately in the spleen and lymph nodes and at low levels in the liver and thymus. Detected in macrophages. {ECO:0000269|PubMed:11722645}. |
Iba1 (isoform 1 and 3) antibody, C-term - GTX89792 from GeneTex
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Anti -AIF1 (G1, IBA1, Allograft Inflammatory Factor 1, Ionized Calcium-binding AdapterMolecule 1, Protein G1) - 139132 from USBiological Life Science
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Anti -AIF1 (G1, IBA1, Allograft Inflammatory Factor 1, Ionized Calcium-binding AdapterMolecule 1, Protein G1) (AP) - 139132-AP from USBiological Life Science
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Anti -AIF1 (G1, IBA1, Allograft Inflammatory Factor 1, Ionized Calcium-binding AdapterMolecule 1, Protein G1) (APC) - 139132-APC from USBiological Life Science
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Anti -AIF1 (G1, IBA1, Allograft Inflammatory Factor 1, Ionized Calcium-binding AdapterMolecule 1, Protein G1) (Biotin) - 139132-Biotin from USBiological Life Science
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Anti -AIF1 (G1, IBA1, Allograft Inflammatory Factor 1, Ionized Calcium-binding AdapterMolecule 1, Protein G1) (FITC) - 139132-FITC from USBiological Life Science
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Anti -AIF1 (G1, IBA1, Allograft Inflammatory Factor 1, Ionized Calcium-binding AdapterMolecule 1, Protein G1) (HRP) - 139132-HRP from USBiological Life Science
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Anti -AIF1 (G1, IBA1, Allograft Inflammatory Factor 1, Ionized Calcium-binding AdapterMolecule 1, Protein G1) (PE) - 139132-PE from USBiological Life Science
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AIF1 Antibody - abx103215 from Abbexa
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Allograft inflammatory factor 1 Antibody - abx109254 from Abbexa
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Allograft inflammatory factor 1 Antibody (Biotin) - abx105120 from Abbexa
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Allograft inflammatory factor 1 Antibody (FITC) - abx106537 from Abbexa
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Allograft inflammatory factor 1 Antibody (HRP) - abx107954 from Abbexa
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Anti-Allograft Inflammatory Factor 1 (AIF1) - 20-4535 from ARP American Research Products
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Anti-IBA1 antibody (isoform 3) - STJ70888 from St John's Laboratory Ltd
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Anti-IBA1 antibody (isoform 1/3) - STJ70166 from St John's Laboratory Ltd
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Allograft Inflammatory Factor 1 (AIF1), Polyclonal Antibody - MBS2017019 from MyBioSource
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allograft inflammatory factor 1 , Polyclonal Antibody - MBS711528 from MyBioSource
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Allograft Inflammatory Factor 1 (AIF1), Polyclonal Antibody - MBS2004585 from MyBioSource
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Allograft Inflammatory Factor 1 (AIF1), Polyclonal Antibody - MBS2006633 from MyBioSource
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Allograft Inflammatory Factor 1 (AIF1), Polyclonal Antibody - MBS2002810 from MyBioSource
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Allograft Inflammatory Factor 1 (AIF1), Polyclonal Antibody - MBS2015390 from MyBioSource
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Allograft Inflammatory Factor 1 (AIF1), Polyclonal Antibody - MBS2005428 from MyBioSource
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Allograft Inflammatory Factor 1 (AIF1), Polyclonal Antibody - MBS2005219 from MyBioSource
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Allograft Inflammatory Factor 1 (AIF1), Polyclonal Antibody - MBS2004978 from MyBioSource
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