Gene Symbol | Aif1 |
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Entrez Gene | 11629 |
Alt Symbol | AI607846, AIF-1, D17H6S50E, G1, Iba1 |
Species | Mouse |
Gene Type | protein-coding |
Description | allograft inflammatory factor 1 |
Other Description | ionized calcium binding adapter molecule 1|ionized calcium-binding adapter molecule 1|testis specific |
Swissprots | O70200 |
Accessions | AAC24189 AAC82481 BAB20757 BAB20758 CAD91187 EDL26636 EDL26637 O70200 AB013745 BAA28216 AF074959 AAC25604 AK006184 BAB24445 AK006562 BAB24654 BC021539 AAH21539 CT010265 CAJ18473 CT010385 CAJ18592 D86382 BAA86387 EF101555 ABK96804 XM_006523503 XP_006523566 XM_006523504 XP_006523567 XM_006525277 XP_006525340 XM_006525278 XP_006525341 XM_006536502 XP_006536565 XM_006536503 XP_006536566 XM_006537235 XP_006537298 XM_006537236 XP_006537299 NM_019467 NP_062340 |
Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. {ECO:0000269|PubMed:10934045, ECO:0000269|PubMed:11500035, ECO:0000269|PubMed:11722645, ECO:0000269|PubMed:11916959, ECO:0000269|PubMed:14756805}. |
Subcellular Location | Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. |
Tissue Specificity | Abundantly expressed in the testis, moderately in the spleen and lymph nodes and at low levels in the liver and thymus. Detected in macrophages. {ECO:0000269|PubMed:11722645}. |
Mouse Aif1 protein - orb244008 from Biorbyt
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Mouse AIF1 Protein - abx065222 from Abbexa
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Allograft Inflammatory Factor 1 (AIF1), Mouse - 20-8436 from ARP American Research Products
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Recombinant Mouse Aif1, His-tagged - Aif1-3277M from Creative Biomart
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Recombinant Allograft Inflammatory Factor 1 (AIF1) - RPC288Mu01 from Cloud-clone
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Recombinant Allograft Inflammatory Factor 1 (AIF1) - RPC288Mu02 from Cloud-clone
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Recombinant Mouse Allograft inflammatory factor 1(Aif1) - CSB-YP001490MO CSB-BP001490MO CSB-MP001490MO from Cusabio
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Recombinant mouse Allograft inflammatory factor 1 - CSB-EP001490MO from Cusabio
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Allograft Inflammatory Factor 1 (AIF1) - RPU140161 from Biomatik
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Allograft Inflammatory Factor 1 - MBS2029741 from MyBioSource
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Allograft Inflammatory Factor 1 (AIF1) - MBS2012246 from MyBioSource
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Allograft inflammatory factor 1(AIF1) - MBS1055052 from MyBioSource
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Recombinant Mouse AIF1 Protein - AIF1-1449M from Creative Biomart
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Recombinant Allograft Inflammatory Factor 1 (AIF1) - RPU40161 from Biomatik
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AIF1 Recombinant Protein (OPCD01222) - OPCD01222 from Aviva Systems Biology
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Recombinant mouse Allograft inflammatory factor 1 - AP70023 from Signalway Antibody
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AIF1 Recombinant Protein (Mouse) (OPCA03795) - OPCA03795 from Aviva Systems Biology
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Recombinant Mouse Allograft inflammatory factor 1 (Aif1) - RPC20877 from Biomatik
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