Gene Symbol | COPZ2 |
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Entrez Gene | 51226 |
Alt Symbol | zeta2-COP |
Species | Human |
Gene Type | protein-coding |
Description | coatomer protein complex, subunit zeta 2 |
Other Description | coatomer subunit zeta-2|nonclathrin coat protein zeta-COP|zeta-2 COP|zeta-2-coat protein |
Swissprots | Q9P299 |
Accessions | EAW94769 Q9P299 AB037938 BAA90670 AB047849 BAB17660 BC015924 AAH15924 BQ002984 BQ576336 DQ893053 ABM83979 DQ896301 ABM87300 HY179834 XM_011524874 XP_011523176 XR_934471 XR_934472 XR_934473 XR_934474 NM_016429 NP_057513 |
Function | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Shows a significant preference for ERGIC and cis-Golgi apparatus compared with trans-Golgi network. {ECO:0000250}. |
Anti-COPZ2 antibody - ab103569 from Abcam
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Anti-COPZ2 Antibody (aa165-195) - LS-C166947 from LifeSpan Bioscience
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Anti-COPZ2 Antibody (aa165-195, AP) - LS-C255266 from LifeSpan Bioscience
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Anti-COPZ2 Antibody (aa165-195, Biotin) - LS-C255268 from LifeSpan Bioscience
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Anti-COPZ2 Antibody (aa165-195) - LS-C320526 from LifeSpan Bioscience
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Anti-COPZ2 Antibody (aa165-195, PE) - LS-C255271 from LifeSpan Bioscience
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Anti-COPZ2 Antibody (aa165-195, Azide-free, HRP) - LS-C255270 from LifeSpan Bioscience
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Anti-COPZ2 Antibody (aa165-195, FITC) - LS-C255269 from LifeSpan Bioscience
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Anti-COPZ2 Antibody (aa165-195, APC) - LS-C255267 from LifeSpan Bioscience
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Coatomer protein complex, subunit zeta 2 Antibody - NBP2-30435 from Novus Biologicals
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ANTI-COPZ2 (C-TERM) antibody produced in rabbit - SAB1301179 from Sigma-Aldrich
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Anti-COPZ2 (1-15) antibody produced in rabbit - SAB1104233 from Sigma-Aldrich
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Anti-COPZ2 antibody produced in rabbit - HPA055999 from Sigma-Aldrich
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Anti-COPZ2 (176-190) antibody produced in rabbit - SAB1104234 from Sigma-Aldrich
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COPZ2 Antibody - C-terminal region (OAAB02592) - OAAB02592 from Aviva Systems Biology
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COPZ2-Antibody-C-term - AP5175b from Abgent, a WuXi AppTec company
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COPZ2 antibody - GTX53526 from GeneTex
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Anti -COPZ2, CT (COPZ2, Coatomer subunit zeta-2, Zeta-2-coat protein) - 034123 from USBiological Life Science
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Anti -COPZ2, CT (COPZ2, Coatomer subunit zeta-2, Zeta-2-coat protein) (AP) - 034123-AP from USBiological Life Science
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Anti -COPZ2, CT (COPZ2, Coatomer subunit zeta-2, Zeta-2-coat protein) (APC) - 034123-APC from USBiological Life Science
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Anti -COPZ2, CT (COPZ2, Coatomer subunit zeta-2, Zeta-2-coat protein) (Azide free) (HRP) - 034123-HRP from USBiological Life Science
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Anti -COPZ2, CT (COPZ2, Coatomer subunit zeta-2, Zeta-2-coat protein) (Biotin) - 034123-Biotin from USBiological Life Science
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Anti -COPZ2, CT (COPZ2, Coatomer subunit zeta-2, Zeta-2-coat protein) (FITC) - 034123-FITC from USBiological Life Science
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Anti -COPZ2, CT (COPZ2, Coatomer subunit zeta-2, Zeta-2-coat protein) (PE) - 034123-PE from USBiological Life Science
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Rabbit Anti-COPZ2 (C-term) - 102-16428 from RayBiotech
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