Pdcd1lg2

Gene Symbol	Pdcd1lg2
Entrez Gene	58205
Alt Symbol	B7-DC, Btdc, F730015O22Rik, PD-L2
Species	Mouse
Gene Type	protein-coding
Description	programmed cell death 1 ligand 2
Other Description	PD-1 ligand 2|PDCD1 ligand 2|butyrophilin B7-DC|butyrophilin-like protein|programmed death ligand 2
Swissprots	Q9WUL5
Accessions	EDL41682 EDL41683 Q9WUL5 AF142780 AAD33892 AK041369 AK089369 BAC40858 AK141111 BAE24564 AK155002 BAE32986 BC104138 AAI04139 BC104139 AAI04140 BY749628 XM_011247309 XP_011245611 NM_021396 NP_067371
Function	Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. {ECO:0000269|PubMed:11224527, ECO:0000269|PubMed:11283156, ECO:0000269|PubMed:12719480}.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Expressed in immature and mature bone marrow- derived dendritic cells and splenic dendritic cells. Highly expressed in placenta, liver and weakly expressed in heart, spleen, lymph nodes and thymus. Also expressed in some tumor cell lines of lymphoid origin. {ECO:0000269|PubMed:11224527, ECO:0000269|PubMed:11283156}.
Top Pathways	Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Recombinant Mouse PD-L2/B7-DC Fc Chimera, CF - 1022-PL-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Mouse Pdcd1lg2, MIgG2a Fc-tagged - Pdcd1lg2-112M from Creative Biomart Category Protein Source CHO cells Species Mouse

Recombinant Mouse Pdcd1lg2, Fc tagged - Pdcd1lg2-7000M from Creative Biomart Category Protein Source Human Cells Species Mouse

Recombinant Mouse Pdcd1lg2, His tagged - Pdcd1lg2-7001M from Creative Biomart Category Protein Source Human Cells Species Mouse

Mouse B7-DC / PD-L2 / CD273 Protein (His Tag) - 50804-M08H-100 from Sino Biological Category Protein Source Human Cells Species Mouse

Mouse B7-DC / PD-L2 / CD273 Protein (Fc Tag) - 50804-M02H-100 from Sino Biological Category Protein Source Human Cells Species Mouse

Recombinant Programmed Cell Death Protein 1 Ligand 2 (PDCD1LG2) - RPA789Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Programmed cell death 1 ligand 2(Pdcd1lg2) - CSB-YP017667MO CSB-EP017667MO CSB-BP017667MO CSB-MP017667MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse PD-L2/B7-DC Fc Chimera Protein, CF - 1022-PL from R&D Systems Category Protein Prices $339.00, $2,500.00 Sizes 100 µg, 1 mg Source Mouse myeloma cell line, NS0-derived Mouse PD-L2 (Leu20-Arg219) Accession # Q9WUL5 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus Species Mouse

Programmed cell death 1 ligand 2 (Pdcd1lg2), Recombinant Protein - MBS1339272 from MyBioSource Category Protein Prices $950.00, $950.00, $1,175.00, $1,175.00, $1,420.00, $1,420.00, $1,885.00, $1,885.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

Recombinant Mouse PD-L2/CD273:Fc Chimera - CRM037 from Cell Science Prices $472.00 Sizes 100 μg Species Mouse

Recombinant Mouse B7-DC / PD-L2 / CD273 Protein (His tag) - PKSM040480 from Elabscience Category Protein Source Human Cells Species Mouse

Recombinant Mouse B7-DC / PD-L2 / CD273 Protein (Fc tag) - PKSM040481 from Elabscience Category Protein Source Human Cells Species Mouse

Recombinant Mouse Pdcd1lg2, Fc-tagged, Biotinylated - Pdcd1lg2-722M from Creative Biomart Category Protein Source Human cells Species Mouse

Recombinant Mouse PD-L2/B7-DC His Tagged Protein, CF - 9107-PL from R&D Systems Category Protein Prices $339.00, $2,360.00 Sizes 100 µg, 1 mg Source Mouse myeloma cell line, NS0-derived Leu20-Arg219, with a C-terminal 6-His tag Species Mouse

Mouse PD-L2 protein - orb348790 from Biorbyt Category Protein Prices $604.00, $3,086.00 Sizes 100 μg, 1 mg Species Mouse

Human CellExp™ PD-L2 / B7-DC, mouse recombinant - P1087 from Biovision Category Protein Prices $85.00, $375.00 Sizes 10 μg, 50 µg Source HEK 293 cells Species Human

PDCD1LG2 Recombinant Protein (OPCD06045) - OPCD06045 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Mouse B7-DC / PD-L2 / CD273 Protein (Fc Tag) - 50804-M02H from ABclonal Category Protein Prices $178.00, $298.00 Sizes 100 µg, 200 µg Source Human Cells Species Mouse

Mouse B7-DC / PD-L2 / CD273 Protein (His Tag) - 50804-M08H from ABclonal Category Protein Prices $178.00, $298.00 Sizes 100 µg, 200 µg Source Human Cells Species Mouse

CD273 [PD-L2] Recombinant Protein - 90-428 from ProSci Category Protein Prices $425.00 Sizes 100 µg Source CHO cells Species Mouse

PD-L2 Recombinant Protein - 92-497 from ProSci Category Protein Prices $275.00 Sizes 50 µg Source Human Cells Species Mouse

PD-L2 Recombinant Protein - 97-023 from ProSci Category Protein Prices $400.00 Sizes 100 µg Source HEK293 cells Species Mouse

PD-L2 Recombinant Protein - 97-021 from ProSci Category Protein Prices $400.00 Sizes 100 µg Source HEK293 cells Species Mouse

PD-L2 Recombinant Protein - 97-022 from ProSci Category Protein Prices $400.00 Sizes 100 µg Source HEK293 cells Species Mouse

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