Name | Recombinant Mouse PD-L2/B7-DC Fc Chimera Protein, CF |
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Supplier | R&D Systems |
Catalog | 1022-PL |
Category | Protein |
Prices | $339.00, $2,500.00 |
Sizes | 100 µg, 1 mg |
Species Reactivities | Mouse |
Nature | Recombinant |
Source | Mouse myeloma cell line, NS0-derived Mouse PD-L2 (Leu20-Arg219) Accession # Q9WUL5 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus |
Purity | >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Bioactivity | Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated mouse T cells. The ED 50 for this effect is 1-6 µg/mL. |
Endotoxin | <0.01 EU per 1 μg of the protein by the LAL method. |
SwissProt/Accession | Q9WUL5 |
Gene | Pdcd1lg2 |
Sequence | Leu20 |
Supplier Page | Shop |
Xiao Y, Yu S, Zhu B, Bedoret D, Bu X, Francisco LM, Hua P, Duke-Cohan JS, Umetsu DT, Sharpe AH, DeKruyff RH, Freeman GJ. J Exp Med. 2014 May 5;211(5):943-59.
Butte MJ, Keir ME, Phamduy TB, Sharpe AH, Freeman GJ. Immunity. 2007 Jul;27(1):111-22. Epub 2007 Jul 12.