| Name | Recombinant Mouse Pdcd1lg2, Fc-tagged, Biotinylated |
|---|---|
| Supplier | Creative Biomart |
| Catalog | Pdcd1lg2-722M |
| Category | Protein |
| Species Reactivities | Mouse |
| Nature | Recombinant |
| Source | Human cells |
| Tag/Conjugation | Fc |
| Purity | >95% judged by SDS-PAGE under reducing condition |
| Bioactivity | Binds to its receptor PD-1 in a functional ELISA. Blocks the ligand PD-L1"s and PD-L2"s binding to its receptor and mediated signaling activity. Shows cross-species binding to human PD-1. |
| Endotoxin | <0.1 EU per 1 μg of purified recombinant protein determined by the LAL method |
| Gene | Pdcd1lg2 |
| Description | The recombinant mouse PD-L2-Fc fusion is expressed as a 438 amino acid protein consisting of Leu20 - Thr220 region of mouse PD-L2 (UniProt accession #Q9WUL5) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
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