CDH2

Gene Symbol CDH2
Entrez Gene 1000
Alt Symbol CD325, CDHN, CDw325, NCAD
Species Human
Gene Type protein-coding
Description cadherin 2, type 1, N-cadherin (neuronal)
Other Description N-cadherin 1|cadherin 2, N-cadherin (neuronal)|cadherin-2|calcium-dependent adhesion protein, neuronal|neural cadherin|neural-cadherin
Swissprots Q14923 Q8N173 B0YIY6 A8MWK3 P19022
Accessions ACA05964 CAA81799 CCD32808 CCE25962 EAX01239 EAX01240 EAX01241 P19022 AA661623 AI675151 AI752179 AI752180 AK302831 BAH13814 AW016710 BC021695 BC036470 AAH36470 BG197310 BX648579 CB105441 CN263272 DA225616 DC403359 EU832318 ACE87575 EU832403 ACE86888 M34064 AAA03236 S42303 AAB22854 X54315 CAA38213 X57548 CAA40773 XM_005258181 XP_005258238 XM_005258182 XP_005258239 XM_011525787 XP_011524089 XM_011525788 XP_011524090 NM_001308176 NP_001295105 NM_001792 NP_001783
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Top Pathways Cell adhesion molecules (CAMs), Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Human N Cadherin peptide - ab18620 from Abcam

Category Peptide
All lanes : Anti-N Cadherin antibody ( ab18203 ) at 1 µg/ml Lane 1 : Rat Brain Lysate Lane 2 : Mouse Brain Lysate Lane 3 : Rat Brain Lysate with Human N Cadherin peptide (ab18620) at 1 µg/ml Lane 4 : Mouse Brain Lysate with Human N Cadherin peptide (ab18620) at 1 µg/ml Lysates/proteins at 20 µg per lane. Secondary Alexa Fluor Goat polyclonal to Rabbit IgG (700) at 1/10000 dilution Performed under reducing conditions. Predicted band size : 135 kDa Observed band size : 135 kDa Additional bands at : 50 kDa (possible truncated form).

Human N Cadherin protein fragment - ab112268 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human N-Cadherin Protein - H00001000-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

N-Cadherin Recombinant Protein - H00001000-G01 from Novus Biologicals

Category Protein
Prices $579.00
Sizes 10 µg
Species Human

Recombinant Human N-Cadherin Fc Chimera, CF - 1388-NC-050 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived

Human CDH2 protein - orb138518 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 50 μg, 100 μg
Source Human Cells
Species Human
SDS-PAGE analysis of human CDH2 protein

Human CDH2 His tag protein - orb83350 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 50 μg, 100 μg
Source Human
Species Human
SDS-PAGE analysis of human CDH2 His tag protein

CD325 Blocking Peptide - abx062394 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine, Chicken, Zebrafish

Human Cadherin, Neuronal Protein - abx065643 from Abbexa

Category Protein
Source E.coli
Species Human

Human Cadherin, Neuronal Protein - abx065647 from Abbexa

Category Protein
Source E.coli
Species Human

Cadherin-2 - H00001000-G01 from Acris Antibodies

Category Protein
Prices $550.00
Sizes 10 µg
Species Human

Cadherin-2 - H00001000-H01 from Acris Antibodies

Category Protein
Prices $570.00
Sizes 2 µg
Source Human HEK293T cells
Species Human

Cadherin-2 - H00001000-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Cadherin-2 - H00001000-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Cadherin, Neuronal (CDH2), Human - 20-7757 from ARP American Research Products

Category Protein
Prices $479.00
Sizes 50 µg
Source E.coli
Species Human

Cadherin, Neuronal (CDH2), Human - 20-7758 from ARP American Research Products

Category Protein
Prices $479.00
Sizes 50 µg
Source E.coli
Species Human

N-cadherin fusion protein - Ag17439 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

N-cadherin fusion protein - ag4752 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

N-cadherin fusion protein - Ag16792 from Proteintech Group

Category Protein
Source E. coli -derived, PGEX-4T
Species Human

N-cadherin fusion protein - ag4996 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human Cadherin 2, Type 1, N-cadherin (Neuronal) - CDH2-87H from Creative Biomart

Category Protein
Source E.coli

Recombinant Human CDH2, His tagged - CDH2-2191H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Recombinant Human CDH2 - CDH2-28769TH from Creative Biomart

Category Protein
Source Wheat germ

Recombinant Human CDH2, His-Fc tagged - CDH2-315H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Recombinant Human CDH2, Fc tagged - CDH2-316H from Creative Biomart

Category Protein
Source NS0 cell
Species Human
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