Gene Symbol | Thap11 |
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Entrez Gene | 59016 |
Alt Symbol | 2810036E22Rik, AB041579, CTG-B43a, CTG-B45d, Ronin |
Species | Mouse |
Gene Type | protein-coding |
Description | THAP domain containing 11 |
Other Description | THAP domain-containing protein 11 |
Swissprots | Q99KZ0 Q3TCZ5 Q9JJD0 |
Accessions | EDL11318 Q9JJD0 AB041579 BAA95063 AK165981 BAE38498 AK166109 AK170457 BAE41810 AK210001 BC003949 AAH03949 BC138966 AAI38967 BC138987 AAI38988 NM_021513 NP_067488 |
Function | Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers. {ECO:0000269|PubMed:18585351}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18585351}. Cytoplasm {ECO:0000269|PubMed:18585351}. Note=May be regulated by shuttling of the protein between the cytoplasm and nucleus. |
Tissue Specificity | Mainly restricted to pluripotent cells of the developing embryo, to oocytes, and to certain regions of the adult brain. {ECO:0000269|PubMed:18585351}. |
Recombinant Mouse THAP domain-containing protein 11(Thap11) - CSB-YP862379MO CSB-EP862379MO CSB-BP862379MO CSB-MP862379MO from Cusabio
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THAP domain-containing protein 11 (Thap11), Recombinant Protein - MBS1383767 from MyBioSource
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Recombinant Mouse THAP11 Protein - THAP11-16730M from Creative Biomart
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