| Gene Symbol |
PSMB11
|
| Entrez Gene |
122706
|
| Alt Symbol |
BETA5T
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) subunit, beta type, 11
|
| Other Description |
proteasome subunit beta 5T|proteasome subunit beta type-11|proteasome subunit beta-5t
|
| Swissprots |
A5LHX3
|
| Accessions |
A5LHX3 AB299437 BAF63540 AK122797 BAG53735 NM_001099780 NP_001093250
|
| Function |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Incorporated instead of PSMB5 or PSMB8, this unit reduces the chymotrypsin-like activity of the proteasome (By similarity). Plays a pivotal role in development of CD8-positive T cells (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000255|PROSITE- ProRule:PRU00809}. Nucleus {ECO:0000250}.
|
| Top Pathways |
Proteasome
|