Gene Symbol | PSMB11 |
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Entrez Gene | 122706 |
Alt Symbol | BETA5T |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) subunit, beta type, 11 |
Other Description | proteasome subunit beta 5T|proteasome subunit beta type-11|proteasome subunit beta-5t |
Swissprots | A5LHX3 |
Accessions | A5LHX3 AB299437 BAF63540 AK122797 BAG53735 NM_001099780 NP_001093250 |
Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Incorporated instead of PSMB5 or PSMB8, this unit reduces the chymotrypsin-like activity of the proteasome (By similarity). Plays a pivotal role in development of CD8-positive T cells (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000255|PROSITE- ProRule:PRU00809}. Nucleus {ECO:0000250}. |
Top Pathways | Proteasome |
PSMB11 (A-5) - sc-514317 from Santa Cruz Biotechnology
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PSMB11 (E-13) - sc-165305 from Santa Cruz Biotechnology
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PSMB11 (D-15) - sc-165304 from Santa Cruz Biotechnology
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PSMB11 (G-15) - sc-165306 from Santa Cruz Biotechnology
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Anti-PSMB11 antibody - C-terminal - ab170832 from Abcam
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Anti-PSMB11 antibody - C-terminal - ab140279 from Abcam
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Anti-PSMB11 Antibody (aa257-286, AP) - LS-C284810 from LifeSpan Bioscience
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Anti-PSMB11 Antibody (aa257-286, APC) - LS-C284811 from LifeSpan Bioscience
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Anti-PSMB11 Antibody (aa257-286, Biotin) - LS-C284812 from LifeSpan Bioscience
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Anti-PSMB11 Antibody (aa257-286, FITC) - LS-C284813 from LifeSpan Bioscience
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Anti-PSMB11 Antibody (aa257-286, Azide-free, HRP) - LS-C284814 from LifeSpan Bioscience
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Anti-PSMB11 Antibody (aa257-286, PE) - LS-C284815 from LifeSpan Bioscience
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Anti-PSMB11 Antibody (aa257-286) - LS-C324355 from LifeSpan Bioscience
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Anti-PSMB11 Antibody (clone b8-17) - LS-C343776 from LifeSpan Bioscience
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Anti-PSMB11 Antibody (aa257-286) - LS-C162229 from LifeSpan Bioscience
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PSMB11 Antibody - NBP2-34158 from Novus Biologicals
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ANTI-PSMB11 (C-TERM) antibody produced in rabbit - SAB1301418 from Sigma-Aldrich
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PSMB11 Antibody - C-terminal region (ARP67249_P050) - ARP67249_P050 from Aviva Systems Biology
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PSMB11-Antibody-C-term - AP11339b from Abgent, a WuXi AppTec company
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PSMB11 Antibody - C-terminal region (OAAB07585) - OAAB07585 from Aviva Systems Biology
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PSMB11 antibody - 70R-19582 from Fitzgerald
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PSMB11 antibody - 55143-1-AP from Acris Antibodies
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PSMB11 (C-term) antibody - AP53487PU-N from Acris Antibodies
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PSMB11 antibody - 55143-1-AP from Proteintech Group
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Anti-PSMB11 (aa 227-276) polyclonal antibody - DPABH-02266 from Creative Diagnostics
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