| Gene Symbol |
ATF7IP2
|
| Entrez Gene |
80063
|
| Alt Symbol |
MCAF2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
activating transcription factor 7 interacting protein 2
|
| Other Description |
ATF7-interacting protein 2|MBD1-containing chromatin associated factor 2|MBD1-containing chromatin-associated factor 2|activating transcription factor 7-interacting protein 2
|
| Swissprots |
Q8N9X8 Q6IS97 Q5U623 Q658U2 Q53EZ7 B2RNR2 Q9H9L6
|
| Accessions |
EAW85183 EAW85184 Q5U623 AK022730 BAB14209 AK093414 BAC04157 AK223492 BAD97212 AK296565 BAG59185 AK299040 BAG61114 AL832987 CAH56323 AY560615 AAT66299 BC033891 AAH33891 BC069695 AAH69695 BC069713 AAH69713 BC069730 AAH69730 BC137079 AAI37080 BC144468 BI459223 XM_006720953 XP_006721016 XM_006720954 XP_006721017 XM_011522666 XP_011520968 NM_001256160 NP_001243089 NM_024997 NP_079273 NR_045815 NR_045816
|
| Function |
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable). {ECO:0000305}.
|
| Subcellular Location |
Nucleus.
|