Gene Symbol | ATF7IP2 |
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Entrez Gene | 80063 |
Alt Symbol | MCAF2 |
Species | Human |
Gene Type | protein-coding |
Description | activating transcription factor 7 interacting protein 2 |
Other Description | ATF7-interacting protein 2|MBD1-containing chromatin associated factor 2|MBD1-containing chromatin-associated factor 2|activating transcription factor 7-interacting protein 2 |
Swissprots | Q8N9X8 Q6IS97 Q5U623 Q658U2 Q53EZ7 B2RNR2 Q9H9L6 |
Accessions | EAW85183 EAW85184 Q5U623 AK022730 BAB14209 AK093414 BAC04157 AK223492 BAD97212 AK296565 BAG59185 AK299040 BAG61114 AL832987 CAH56323 AY560615 AAT66299 BC033891 AAH33891 BC069695 AAH69695 BC069713 AAH69713 BC069730 AAH69730 BC137079 AAI37080 BC144468 BI459223 XM_006720953 XP_006721016 XM_006720954 XP_006721017 XM_011522666 XP_011520968 NM_001256160 NP_001243089 NM_024997 NP_079273 NR_045815 NR_045816 |
Function | Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable). {ECO:0000305}. |
Subcellular Location | Nucleus. |
MCAF2 (H-300) - sc-135301 from Santa Cruz Biotechnology
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MCAF2 (N-17) - sc-164973 from Santa Cruz Biotechnology
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MCAF2 (T-16) - sc-164977 from Santa Cruz Biotechnology
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Anti-MCAF2 antibody - ab107967 from Abcam
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Anti-MCAF2 antibody - N-terminal - ab136698 from Abcam
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Anti-ATF7IP2 Antibody (aa325-355, APC) - LS-C237470 from LifeSpan Bioscience
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Anti-ATF7IP2 Antibody (aa325-355, FITC) - LS-C237472 from LifeSpan Bioscience
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Anti-ATF7IP2 Antibody (aa325-355, Biotin) - LS-C237471 from LifeSpan Bioscience
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Anti-ATF7IP2 Antibody (aa325-355, PE) - LS-C237474 from LifeSpan Bioscience
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Anti-ATF7IP2 Antibody (aa325-355, AP) - LS-C237468 from LifeSpan Bioscience
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Anti-ATF7IP2 Antibody (aa325-355, Azide-free, HRP) - LS-C248781 from LifeSpan Bioscience
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Anti-ATF7IP2 Antibody (aa100-149) - LS-C169855 from LifeSpan Bioscience
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Anti-ATF7IP2 Antibody (aa325-355) - LS-C322897 from LifeSpan Bioscience
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Anti-ATF7IP2 Antibody (aa318-347) IHC-plus™ - LS-B12078 from LifeSpan Bioscience
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ATF7IP2 Antibody - NBP1-94029 from Novus Biologicals
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ATF7IP2 Antibody - NBP1-94028 from Novus Biologicals
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Anti-ATF7IP2 antibody produced in rabbit - HPA041228 from Sigma-Aldrich
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ANTI-MCAF2 (CENTER) antibody produced in rabbit - SAB1306455 from Sigma-Aldrich
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Anti-ATF7IP2 antibody produced in rabbit - HPA041156 from Sigma-Aldrich
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ATF7IP2 Antibody - N-terminal region (ARP67011_P050) - ARP67011_P050 from Aviva Systems Biology
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ATF7IP2 Antibody - middle region (OAAB00522) - OAAB00522 from Aviva Systems Biology
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MCAF2-Antibody-Center - AP10509c from Abgent, a WuXi AppTec company
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ATF7IP2 antibody - GTX53623 from GeneTex
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Anti -MCAF2, ID (ATF7IP2, MCAF2, Activating transcription factor 7-interacting protein 2,MBD1-containing chromatin-associated factor 2) - 038259 from USBiological Life Science
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Anti -MCAF2, ID (ATF7IP2, MCAF2, Activating transcription factor 7-interacting protein 2,MBD1-containing chromatin-associated factor 2) (AP) - 038259-AP from USBiological Life Science
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