Gene Symbol | SRCAP |
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Entrez Gene | 10847 |
Alt Symbol | DOMO1, EAF1, FLHS, SWR1 |
Species | Human |
Gene Type | protein-coding |
Description | Snf2-related CREBBP activator protein |
Other Description | Snf2-related CBP activator protein|Swi2/Snf2-related ATPase homolog, domino homolog 1|domino homolog 2|helicase SRCAP |
Swissprots | Q6ZRS2 Q9Y5L9 Q7Z744 B0JZA6 O15026 |
Accessions | EAW52213 EAW52214 Q6ZRS2 AB621816 BAK64152 AF143946 AAD39760 AK023808 BAG51225 AK025382 AK126463 BAC86558 AK128030 BAC87237 AU140541 BC025284 BC063578 AAH63578 BC172428 AAI72428 BM677852 DA109400 NM_006662 NP_006653 |
Function | Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription. {ECO:0000269|PubMed:10347196, ECO:0000269|PubMed:11522779, ECO:0000269|PubMed:14500758, ECO:0000269|PubMed:16024792, ECO:0000269|PubMed:16634648, ECO:0000269|PubMed:17617668}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00549, ECO:0000269|PubMed:10702287}. |
SRCAP (C-13) - sc-133310 from Santa Cruz Biotechnology
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SRCAP (T-15) - sc-133312 from Santa Cruz Biotechnology
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Anti-SRCAP antibody - ab99408 from Abcam
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Anti-SRCAP antibody - C-terminal - ab201149 from Abcam
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Anti-SWR1 / SRCAP Antibody (aa309-322) IHC-plus™ - LS-B10337 from LifeSpan Bioscience
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Anti-SWR1 / SRCAP Antibody (Internal) - LS-C112885 from LifeSpan Bioscience
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SRCAP Antibody - NBP1-84063 from Novus Biologicals
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SRCAP Antibody - NBP1-45244 from Novus Biologicals
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SRCAP Polyclonal Antibody - bs-12119R from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12119R-A350 from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12119R-A488 from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12119R-A555 from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12119R-A647 from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, Cy3 Conjugated - bs-12119R-Cy3 from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, Cy5 Conjugated - bs-12119R-Cy5 from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, Cy5.5 Conjugated - bs-12119R-Cy5.5 from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, Cy7 Conjugated - bs-12119R-Cy7 from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, FITC Conjugated - bs-12119R-FITC from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, Biotin Conjugated - bs-12119R-Biotin from Bioss
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Rabbit Anti-SRCAP Polyclonal Antibody, HRP Conjugated - bs-12119R-HRP from Bioss
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Anti-SRCAP antibody produced in rabbit - HPA028929 from Sigma-Aldrich
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SRCAP-Antibody-internal-region - AF3030a from Abgent, a WuXi AppTec company
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SRCAP-aa309-322-Antibody-internal-region-near-N-Trminus - AF3617a from Abgent, a WuXi AppTec company
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SRCAP antibody - orb20374 from Biorbyt
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SRCAP antibody - orb158491 from Biorbyt
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