Aimp1

Gene Symbol Aimp1
Entrez Gene 13722
Alt Symbol 9830137A06Rik, AIMP1/p43, EMAPII, Emap2, Scye1, p43
Species Mouse
Gene Type protein-coding
Description aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
Other Description ARS inducible multifunctional protein 1|aminoacyl tRNA synthase complex-interacting multifunctional protein 1|endothelial monocyte activating polypeptide 2|multisynthase complex auxiliary component p43|multisynthetase complex auxiliary component p43|small inducible cytokine subfamily E, member 1
Swissprots P31230 Q60659
Accessions EDL12194 P31230 AK036573 AK050571 AK087932 BAC40045 AK133859 BAE21893 AK160506 BAE35830 BC002054 AAH02054 BY256548 BY631162 U10118 AAA62203 NM_007926 NP_031952
Function Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1- mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle. Secreted. Endoplasmic reticulum. Golgi apparatus. Note=Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels. Also secreted in response to hypoxia and both apoptotic and necrotic cell death.
Tissue Specificity Highly expressed in salivary glands and pancreatic alpha cells in the adult (at protein level). In the embryo, expressed primarily at sites of tissue remodeling such as ganglia, developing bones and teeth. {ECO:0000269|PubMed:17001013, ECO:0000269|PubMed:9770485}.

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (SCYE1), Mouse, ELISA Kit - E03A1968 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Aimp1, Mouse, ELISA Kit - E2214m from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t
Range 78-5000 pg/mL

Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1), Mouse, ELISA Kit - SEL761Mu from ARP American Research Products

Category ELISA Kit
Prices $812.00
Sizes 96 t
Sensitivity 14.8pg/mL
Range 31.2-2,000pg/mL

ELISA Kit for Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) - SEL761Mu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 12.4pg/mL.
Range 31.25-2000pg/mL The standard curve concentrations used for the ELISA's were 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL

Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1), Mouse, ELISA Kit - DL-AIMP1-Mu from ARP American Research Products

Category ELISA Kit
Prices $685.00
Sizes 96 t
Range 31.2-2,000 pg/mL

Mouse AIMP1 ELISA Kit - abx575645 from Abbexa

Category ELISA Kit
Sensitivity 14.8 pg/ml
Range 31.25 pg/ml - 2000 pg/ml

Aimp1 - EKM1482 from Nordic BioSite

Sensitivity 46.9pg/ml
Range 78-5000pg/ml

Mouse Aimp1 ELISA Kit - E043611 from Biobool

Category ELISA Kit

Mouse SCYE1 ELISA Kit - E043613 from Biobool

Category ELISA Kit
Sensitivity 0.1 ng/mL.

AIMP1 ELISA Kit (Mouse) (OKEH03479) - OKEH03479 from Aviva Systems Biology

Category ELISA Kit
Prices $425.00
Sizes 96 wells
Sensitivity 39 pg/mL
Range 78 - 5,000 pg/mL

Mouse Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 ELISA Kit - EK4397 from Signalway Antibody

Category ELISA Kit
Prices $599.00
Sizes 1x96t
Sensitivity less than 0.065ng/mL
Range 0.156-10 ng/mL

Anti-Monocyte antibody, ELISA Kit - MBS2608796 from MyBioSource

Category ELISA Kit
Prices $300.00, $475.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, ELISA Kit - MBS2883846 from MyBioSource

Category ELISA Kit
Prices $380.00, $500.00, $2,170.00, $3,840.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 78-5000 pg/mL

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, ELISA Kit - MBS9428223 from MyBioSource

Category ELISA Kit
Prices $555.00
Sizes 96 tests
Range 78-5000 pg/mL

Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1), ELISA Kit - MBS453039 from MyBioSource

Category ELISA Kit
Prices $455.00, $605.00, $2,685.00, $5,220.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity <14.8pg/mL
Range 31.2-2000pg/mL
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