UBC

Gene Symbol UBC
Entrez Gene 7316
Alt Symbol HMG20
Species Human
Gene Type protein-coding
Description ubiquitin C
Other Description polyubiquitin-C
Swissprots Q9UEF2 Q9UEK8 P62988 P0CG48 Q6LBL4 Q6LDU5 Q8WYN8 Q9UPK7 Q9BX98 Q9BWD6 Q9UEG1
Accessions BAA09860 BAA23486 BAC56951 BAM77032 BAM77033 BAM77034 BAM77035 BAM77036 BAM77037 EAW98463 EAW98464 EAW98465 EAW98466 P0CG48 AB009010 BAA23632 AB209782 BAD93019 AF052164 AK026846 AK056939 BAB71316 AK092983 AK097415 AK098827 AK129749 AK291539 BAF84228 AL117514 CAB55973 AW069329 AY732488 AAV33127 AY819759 AAV68344 BC000449 BC008955 AAH08955 BC014880 AAH14880 BC039193 AAH39193 BC080583 AAH80583 BC093445 BE873233 BF793240 BU195276 DB077241 DC395997 M17597 AAA36787 M26880 AAA36789 NM_021009 NP_066289
Function Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription fac
Subcellular Location Ubiquitin: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Top Pathways PPAR signaling pathway

Anti-UBC / Ubiquitin C Antibody (aa36-66) IHC-plus™ - LS-B3621 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-UBC / Ubiquitin C antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3621 concentration 10 ug/ml.

Anti-UBC / Ubiquitin C Antibody (aa1-32) IHC-plus™ - LS-B3386 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-UBC / Ubiquitin C antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3386 concentration 10 ug/ml.

Anti-UBC / Ubiquitin C Antibody - LS-C2924 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of aggresomes of mouse L-cells treated with lactacysteine.

Ubiquitin Antibody (Ubi-1) - NB300-130 from Novus Biologicals

Prices $129.00, $369.00
Sizes 25 µl, 100 µl
Host Mouse
Clonality Monoclonal
Clone Ubi-1
Western Blot: Ubiquitin Antibody (Ubi-1) [NB300-130] - Western blot of Ubiquitin expression on (Lane 1) poly-ubiquitin (lys63 linked), (Lane 2) pure ubiquitin and crude homogenates of adult rat, (Lane 3) cortex, (Lane 4) cerebellum and (Lane 5) brain stem.

UBA52 Antibody - NB300-263 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UBA52 Antibody [NB300-263] - Detection of Ubiquitin by Western Blotting of Products from an Ubiquitination Assay and Purified Ubiquitin. Samples: A) Ubiquitination assay was performed as described in Zhang et al., 2004, Mol. Cell. Biol. 24(24):10941-10953. B) Purified human ubiquitin was applied in decreasing amounts from 5 to 0.1 mcg. Antibody: Affinity purified rabbit anti-Ubiquitin antibody NB 300-263 used at 0.4 mcg/ml for Western Blot. Detection: Alkaline phosphatase conjugated secondary antibody and development with NBT/BCIP for 10 minutes (A and B).

Ubiquitin Antibody - NBP1-23015 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Ubiquitin Antibody [NBP1-23015] - Sample: FFPE section of mouse colon carcinoma. Antibody: Affinity purified rabbit anti-Ubiquitin (Cat. No. IHC-00420) used at a dilution of 1:250.

UBA52 Antibody - NBP2-29880 from Novus Biologicals

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UBA52 Antibody [NBP2-29880] - Bacterial cell lysate containing recombinant UBB+1 was analyzed with anti-UBB+1 (Ubi2a) (1:5000). Arrow indicates UBB+1 (11kDa).

UBA52 Antibody - NBP1-55537 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: UBA52 Antibody [NBP1-55537] - Analysis of paraffin-embedded human breast carcinoma tissue, using UBA52 Antibody. The picture on the right is treated with the synthesized peptide.

Ubiquitin Polyclonal Antibody - bs-1549R from Bioss

Prices $279.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human breast cancer labeled with Anti-Ubiquitin/UBC/UB Polyclonal Antibody, Unconjugated (bs-1549R) followed by conjugation to the secondary antibody and DAB staining

Anti-Ubiquitin antibody produced in chicken - GW10073F from Sigma-Aldrich

Host Chicken
Clonality Polyclonal

Ubiquitin-Antibody - AP1229A from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of anti-Ubiquitin Pab (Cat. #AP1229a) in HeLa cell lysate. Ubiquitin (Arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Ubiquitin-Antibody-N-term - AP1228a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of anti-Ubiquitin Pab (Cat. #AP1228a) in HeLa cell lysate. Ubiquitin (Arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Ubiquitin-Antibody-C-term - AJ1807a from Abgent, a WuXi AppTec company

Host Rabbit
Clonality Monoclonal
Clone EP296Y
A. Western blot analysis on Hela cell lysate using anti-Ubiquitin (C-term) RabMAb (Cat. #AJ1807a), dilution 1:2,000.

UBC Antibody (OABF00752) - OABF00752 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Ubiquitin antibody (RPE) - orb151484 from Biorbyt

Prices $553.00
Sizes 200 μl
Host Rabbit
Clonality Polyclonal

Ubiquitin antibody (ATTO-633) - orb147647 from Biorbyt

Prices $561.00
Sizes 200 μg
Host Mouse
Clonality Monoclonal
Clone 6C11-B3

Ubiquitin antibody (FITC) - orb147501 from Biorbyt

Prices $536.00
Sizes 200 μg
Host Mouse
Clonality Monoclonal
Clone 5B9-B3

Ubiquitin antibody (ATTO 390) - orb181963 from Biorbyt

Prices $323.00
Sizes 100 μg
Host Mouse
Clonality Monoclonal

Ubiquitin antibody (ATTO-565) - orb147492 from Biorbyt

Prices $561.00
Sizes 200 μg
Host Mouse
Clonality Monoclonal

UBC Antibody (OALA03300) - OALA03300 from Aviva Systems Biology

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

UBC antibody - 70R-21093 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Ubiquitin Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-1549R-A350 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Ubiquitin Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-1549R-A488 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Ubiquitin Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-1549R-A555 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Ubiquitin Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-1549R-A647 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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