UBC

Gene Symbol UBC
Entrez Gene 7316
Alt Symbol HMG20
Species Human
Gene Type protein-coding
Description ubiquitin C
Other Description polyubiquitin-C
Swissprots Q9UEF2 Q9UEK8 P62988 P0CG48 Q6LBL4 Q6LDU5 Q8WYN8 Q9UPK7 Q9BX98 Q9BWD6 Q9UEG1
Accessions BAA09860 BAA23486 BAC56951 BAM77032 BAM77033 BAM77034 BAM77035 BAM77036 BAM77037 EAW98463 EAW98464 EAW98465 EAW98466 P0CG48 AB009010 BAA23632 AB209782 BAD93019 AF052164 AK026846 AK056939 BAB71316 AK092983 AK097415 AK098827 AK129749 AK291539 BAF84228 AL117514 CAB55973 AW069329 AY732488 AAV33127 AY819759 AAV68344 BC000449 BC008955 AAH08955 BC014880 AAH14880 BC039193 AAH39193 BC080583 AAH80583 BC093445 BE873233 BF793240 BU195276 DB077241 DC395997 M17597 AAA36787 M26880 AAA36789 NM_021009 NP_066289
Function Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription fac
Subcellular Location Ubiquitin: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Top Pathways PPAR signaling pathway

UBC CRISPR/Cas9 KO Plasmid (h) - sc-411048 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC HDR Plasmid (h) - sc-411048-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC Double Nickase Plasmid (h) - sc-411048-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC Double Nickase Plasmid (h2) - sc-411048-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC CRISPR Activation Plasmid (h) - sc-411048-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC CRISPR Activation Plasmid (h2) - sc-411048-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC Lentiviral Activation Particles (h) - sc-411048-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC Lentiviral Activation Particles (h2) - sc-411048-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UBC siRNA (h) - sc-106655 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UBC shRNA Plasmid (h) - sc-106655-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UBC shRNA (h) Lentiviral Particles - sc-106655-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU052331 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2469 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2469 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

shRNA set against Human UBC (NM_021009.5) - SHH438808 from Creative biogene

Category siRNA
Species Reactivities Human

UBC miRNA 3'UTR clone - MiUTR3H-02354 from Creative biogene

Species Reactivities Human
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