Gene Symbol | HECTD3 |
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Entrez Gene | 79654 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | HECT domain containing E3 ubiquitin protein ligase 3 |
Other Description | E3 ubiquitin-protein ligase HECTD3 |
Swissprots | Q5T447 B3KRH4 Q9H783 Q5T448 B3KPV7 |
Accessions | EAX07009 EAX07010 Q5T447 AA001245 AK056545 BAG51742 AK056873 BAG51819 AK091583 BAG52386 AK096462 BAG53296 AK301124 BAG62718 AW170440 BC012829 BC019105 AAH19105 BC126352 AAI26353 BC130470 AAI30471 BQ215795 CA314393 DA332198 XM_011542140 XP_011540442 NM_024602 NP_078878 |
Function | E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000250}. |
HECTD3 (C-19) - sc-243012 from Santa Cruz Biotechnology
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HECTD3 (K-17) - sc-243011 from Santa Cruz Biotechnology
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HECTD3 (L-18) - sc-243010 from Santa Cruz Biotechnology
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Anti-HECTD3 antibody - ab67985 from Abcam
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Anti-HECTD3 antibody - C-terminal - ab173122 from Abcam
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Anti-HECTD3 Antibody (aa740-769, AP) - LS-C259723 from LifeSpan Bioscience
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Anti-HECTD3 Antibody (aa740-769, PE) - LS-C259727 from LifeSpan Bioscience
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Anti-HECTD3 Antibody (aa740-769, APC) - LS-C259726 from LifeSpan Bioscience
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Anti-HECTD3 Antibody (aa740-769, FITC) - LS-C259965 from LifeSpan Bioscience
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Anti-HECTD3 Antibody (aa740-769, Biotin) - LS-C259963 from LifeSpan Bioscience
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Anti-HECTD3 Antibody (aa740-769, Azide-free, HRP) - LS-C259966 from LifeSpan Bioscience
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Anti-HECTD3 Antibody - LS-C308205 from LifeSpan Bioscience
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Anti-HECTD3 Antibody (aa739-769) - LS-C321917 from LifeSpan Bioscience
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Anti-HECTD3 Antibody (aa740-769) - LS-C159819 from LifeSpan Bioscience
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HECTD3 Antibody - NBP1-82153 from Novus Biologicals
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HECTD3 Antibody - H00079654-B01P from Novus Biologicals
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HECTD3 Polyclonal Antibody - bs-15448R from Bioss
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Anti-HECTD3 antibody produced in rabbit - HPA027467 from Sigma-Aldrich
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Anti-HECTD3 antibody produced in mouse - SAB1407955 from Sigma-Aldrich
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HECTD3-Antibody-C-term - AP17451b from Abgent, a WuXi AppTec company
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HECTD3 antibody - GTX53579 from GeneTex
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HECTD3 Antibody - C-terminal region (OAAB12882) - OAAB12882 from Aviva Systems Biology
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Anti -HECTD3 (E3 Ubiquitin-protein Ligase HECTD3, HECT Domain-containing Protein 3,FLJ21156, FLJ31983, MGC161630, RP11-69J16.1) - 127789 from USBiological Life Science
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Anti -HECTD3, CT (HECTD3, E3 ubiquitin-protein ligase HECTD3, HECT domain-containingprotein 3) - 036497 from USBiological Life Science
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Anti -HECTD3, CT (HECTD3, E3 ubiquitin-protein ligase HECTD3, HECT domain-containingprotein 3) (AP) - 036497-AP from USBiological Life Science
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