MINPP1

Gene Symbol MINPP1
Entrez Gene 9562
Alt Symbol HIPER1, MINPP2, MIPP
Species Human
Gene Type protein-coding
Description multiple inositol-polyphosphate phosphatase 1
Other Description 2,3-BPG phosphatase|2,3-bisphosphoglycerate 3-phosphatase|inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase|ins(1,3,4,5)P(4) 3-phosphatase|multiple inositol polyphosphate histidine phosphatase, 1|multiple inositol polyphosphate phosphatase 1|multiple inositol polyphosphate phosphatase 2
Swissprots Q9UNW1 Q59EJ2 O95172 O95286 Q9UGA3 F5H683
Accessions AAD02438 EAW50185 EAW50186 Q9UNW1 AB209819 BAD93056 AF046914 AAD02437 AF084943 AAD09751 AF084944 AAD09752 AK304624 BAG65406 AK309176 AK312937 BAG35779 AL050356 CAB43673 AW243689 AY358938 AAQ89297 BC032504 AAH32504 BU173009 DA295586 HQ447272 ADQ31759 XM_006718078 XP_006718141 XM_011540379 XP_011538681 XR_945884 NM_001178117 NP_001171588 NM_001178118 NP_001171589 NM_004897 NP_004888
Function Acts as a phosphoinositide 5- and phosphoinositide 6- phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3- phosphoglycerate. May play a role in bone development (endochondral ossification). {ECO:0000269|PubMed:18413611}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}.
Tissue Specificity Widely expressed with highest levels in kidney, liver and placenta. {ECO:0000269|PubMed:9923613}.
Top Pathways Glycolysis / Gluconeogenesis, Inositol phosphate metabolism

MIPP (A-4) - sc-374456 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MIPP (A-4): sc-374456. Western blot analysis of MIPP expression in KNRK whole cell lysate.

MIPP (A-8) - sc-514214 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MIPP (A-8): sc-514214. Western blot analysis of MIPP expression in Hep G2 (A), MIA PaCa-2 (B), HeLa (C) and K-562 (D) whole cell lysates.

MIPP (H-95) - sc-366027 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MIPP (K-18) - sc-10405 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MIPP (K-18): sc-10405. Western blot analysis of MIPP expression in Hep G2 (A), MIA PaCa (B) and KNRK (C) whole cell lysates.

MIPP (N-14) - sc-10399 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MIPP (N-14): sc-10399. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tumor showing cytoplasmic and extracellular localization.

MIPP (S-20) - sc-10403 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MIPP (S-20): sc-10403. Western blot analysis of MIPP expression in Hep G2 whole cell lysate.

Anti-MINPP1 antibody - ab97602 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-MINPP1 antibody (ab97602) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-MINPP1 antibody - ab107557 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MINPP1 antibody (ab107557) at 1/100 dilution + K562 cell line lysates at 35 µg

Anti-MINPP1 antibody - ab137306 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MINPP1 antibody (ab137306) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-MINPP1 Antibody (aa370-398, AP) - LS-C263162 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (Ile360) - LS-C193152 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa370-398, APC) - LS-C263163 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa370-398, Biotin) - LS-C263164 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa370-398, FITC) - LS-C263165 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa370-398, Azide-free, HRP) - LS-C263166 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa370-398, PE) - LS-C263167 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa28-55, AP) - LS-C263168 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa28-55, APC) - LS-C263169 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa28-55, FITC) - LS-C263171 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa28-55, Biotin) - LS-C263172 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa28-55, Azide-free, HRP) - LS-C263173 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa28-55, PE) - LS-C263174 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa369-348) - LS-C323007 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa311-360) - LS-C292185 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MINPP1 Antibody (aa328-377) - LS-C120103 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from 293 cells, using MINPP1 Antibody. The lane on the right is treated with the synthesized peptide.
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