Gene Symbol | COPG2 |
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Entrez Gene | 26958 |
Alt Symbol | 2-COP, gamma-2-COP |
Species | Human |
Gene Type | protein-coding |
Description | coatomer protein complex, subunit gamma 2 |
Other Description | coat protein, nonclathrin, gamma-2-cop|coatomer subunit gamma-2|gamma-2-coat protein |
Swissprots | Q2NLA0 Q8WVW8 Q54AC3 A6NH74 Q9UBF2 |
Accessions | AAL17778 EAL24085 EAW83769 Q9UBF2 AB047847 BAB17658 AF157833 AAF14271 AF207598 AAF19433 AF308295 AAG48262 AI566718 AK002086 BAA92078 AK022934 BAB14315 AK024414 BAG51296 AK291409 BAF84098 AL162012 CAB82364 BC017443 AAH17443 BC110796 AAI10797 BG470623 BG704011 BX089636 BX353590 HY355769 NM_001290033 NP_001276962 NM_012133 NP_036265 |
Function | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Tends to be more abundant in the trans-Golgi network compared to the cis-Golgi. {ECO:0000250}. |
Human COPG2 full length protein - ab162042 from Abcam
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Human COPG2 protein fragment - ab162043 from Abcam
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COPG2 Antibody Blocking Peptide - LS-E19774 from LifeSpan Bioscience
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Recombinant Human COPG2 Protein - H00026958-Q01 from Novus Biologicals
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Recombinant Human COPG2 Protein - H00026958-P01 from Novus Biologicals
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COPG2-Antibody-C-term-Blocking-Peptide - BP13114b from Abgent, a WuXi AppTec company
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COPG2 Blocking Peptide - 33R-6111 from Fitzgerald
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Coatomer subunit gamma-2 - H00026958-Q01-10 from Acris Antibodies
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Coatomer subunit gamma-2 - H00026958-Q01-25 from Acris Antibodies
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COPG2 - H00026958-P01-02 from Acris Antibodies
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Coatomer subunit gamma-2 Control Peptide - SP5478CP from Acris Antibodies
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COPG2 fusion protein - ag9058 from Proteintech Group
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COPG2 fusion protein - Ag9034 from Proteintech Group
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Recombinant Human Coatomer subunit gamma-2(COPG2) ,partial - CSB-YP866200HU CSB-EP866200HU CSB-BP866200HU CSB-MP866200HU from Cusabio
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Coatomer subunit gamma-2 - TP323372 from Acris Antibodies
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COPG2 Peptide, Human - M34GP03498H from Creative Peptides
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Coatomer subunit gamma-2 (COPG2), partial, Recombinant Protein - MBS1302688 from MyBioSource
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