Gene Symbol | COPG2 |
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Entrez Gene | 26958 |
Alt Symbol | 2-COP, gamma-2-COP |
Species | Human |
Gene Type | protein-coding |
Description | coatomer protein complex, subunit gamma 2 |
Other Description | coat protein, nonclathrin, gamma-2-cop|coatomer subunit gamma-2|gamma-2-coat protein |
Swissprots | Q2NLA0 Q8WVW8 Q54AC3 A6NH74 Q9UBF2 |
Accessions | AAL17778 EAL24085 EAW83769 Q9UBF2 AB047847 BAB17658 AF157833 AAF14271 AF207598 AAF19433 AF308295 AAG48262 AI566718 AK002086 BAA92078 AK022934 BAB14315 AK024414 BAG51296 AK291409 BAF84098 AL162012 CAB82364 BC017443 AAH17443 BC110796 AAI10797 BG470623 BG704011 BX089636 BX353590 HY355769 NM_001290033 NP_001276962 NM_012133 NP_036265 |
Function | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Tends to be more abundant in the trans-Golgi network compared to the cis-Golgi. {ECO:0000250}. |
γ2-COP (C-20) - sc-14165 from Santa Cruz Biotechnology
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γ2-COP (S-21) - sc-23204 from Santa Cruz Biotechnology
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γ2-COP (A-13) - sc-23203 from Santa Cruz Biotechnology
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Anti-COPG2 antibody - ab98055 from Abcam
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Anti-COPG2 Antibody (N-Terminus) - LS-C107743 from LifeSpan Bioscience
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COPG2 Antibody - NBP1-57636 from Novus Biologicals
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COPG2 Antibody - H00026958-A01 from Novus Biologicals
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Anti-COPG2, (N-terminal) antibody produced in rabbit - SAB2104939 from Sigma-Aldrich
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COPG2 antibody - N-terminal region (ARP54845_P050) - ARP54845_P050 from Aviva Systems Biology
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COPG2 antibody, N-term - GTX45371 from GeneTex
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Anti -COPG2 (Coatomer Subunit gamma-2, 2-COP, gamma-2-COP) - 210209 from USBiological Life Science
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COPG2 Polyclonal Antibody - A4630 from ABclonal
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COPG2 antibody - 70R-16512 from Fitzgerald
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COPG2 antibody - 70R-3831 from Fitzgerald
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COPG2 Antibody - abx003483 from Abbexa
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Coatomer subunit gamma-2 antibody - 16111-1-AP from Acris Antibodies
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Coatomer subunit gamma-2 antibody - H00026958-A01 from Acris Antibodies
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Anti-COPG2, Polyclonal Antibody - 25-A4630 from ARP American Research Products
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COPG2 antibody - 16111-1-AP from Proteintech Group
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COPG2 antibody - STJ23199 from St John's Laboratory Ltd
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COPG2, Polyclonal Antibody - MBS2522123 from MyBioSource
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COPG2 - MBS128956 from MyBioSource
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COPG2 - A4630 from NeoScientific
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COPG2 Antibody - GWB-MT577A from Genway Biotech
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coatomer protein complex, subunit gamma 2 , Polyclonal Antibody - MBS716167 from MyBioSource
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