APOBR

Gene Symbol	APOBR
Entrez Gene	55911
Alt Symbol	APOB100R, APOB48R
Species	Human
Gene Type	protein-coding
Description	apolipoprotein B receptor
Other Description	apoB-48R\|apolipoprotein B-100 receptor\|apolipoprotein B-48 receptor\|apolipoprotein B100 receptor\|apolipoprotein B48 receptor
Swissprots	Q0VD81 H3BU97 Q0VD83 Q9NPJ9 Q8NC15
Accessions	AAF76256 EAW52278 EAW52279 EAW52280 Q0VD83 AF141332 AAF76255 AF141334 AAF78765 AK025123 AK075085 BC119786 AAI19787 BC119788 AAI19789 NM_018690 NP_061160
Function	Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG- VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages. {ECO:0000269\|PubMed:10852956, ECO:0000269\|PubMed:15591219, ECO:0000269\|PubMed:9633939}.
Subcellular Location	Cell membrane {ECO:0000269\|PubMed:10191299, ECO:0000269\|PubMed:7619811}; Peripheral membrane protein {ECO:0000269\|PubMed:10191299, ECO:0000269\|PubMed:7619811}. Note=Binds monocyte-macrophage membrane. Thought to be anchored in the membrane through an interaction with an integral membrane protein.
Tissue Specificity	Expressed in peripheral blood leukocytes > bone marrow = spleen > lymph node, and only faintly visible in appendix and thymus. Expressed in the brain, heart, kidney, liver, lung, pancreas, and placenta. Expressed primarily by reticuloendothelial cells: monocytes, macrophages, and endothelial cells. Expressed in atherosclerotic lesion foam cells. {ECO:0000269\|PubMed:10191299, ECO:0000269\|PubMed:10852956}.

apob48r (Q-15) - sc-163699 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-APOB48R antibody - ab125128 from Abcam

Prices	$407.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

ab125128 at 1/100 dilution staining APOB48R in formalin-fixed, paraffin-embedded Human liver tissue by Immunohistochemistry.

Anti-APOB48R antibody - ab138538 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-APOB48R antibody (ab138538) at 1/100 dilution + A549 cell lysate at 35 µg

Anti-APOB48R antibody - ab57458 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Western blot against tagged recombinant protein immunogen using ab57458 APOB48R antibody at 1ug/ml.

Anti-APOBR / APOB48R Antibody (aa930-942) - LS-C87327 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-APOBR / APOB48R Antibody (clone 2D7) - LS-C133787 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2D7

Anti-APOBR / APOB48R Antibody (aa596-622, Biotin) - LS-C232752 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-APOBR / APOB48R Antibody (aa596-622, AP) - LS-C232751 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-APOBR / APOB48R Antibody (aa596-622, APC) - LS-C232753 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-APOBR / APOB48R Antibody (aa596-622, FITC) - LS-C232754 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-APOBR / APOB48R Antibody (aa596-622, PE) - LS-C232755 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-APOBR / APOB48R Antibody (aa596-622, Azide-free, HRP) - LS-C249441 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-APOBR / APOB48R Antibody (aa595-622) - LS-C319543 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-APOBR / APOB48R Antibody (aa596-622) - LS-C159093 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

APOB48R Antibody western blot of A549 cell line lysates (35 ug/lane). The APOB48R antibody detected the APOB48R protein (arrow).

Anti-APOBR / APOB48R Antibody (aa780-1088, clone 2G6) - LS-C340174 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2G6

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOBR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOBR.

Anti-APOBR / APOB48R Antibody (aa780-1088, clone 3D11) - LS-C340185 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	3D11

Anti-APOBR / APOB48R Antibody (aa780-1088, clone 2E6) - LS-C340175 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2E6

Western blot of extracts (10ug) from 5 different cell lines and 4 human tissue by using anti-APOBR monoclonal antibody (1: HeLa; 2: HepG2; 3: K562; 4: Mcf7; 5: SVT2; 6: Liver; 7: Testis; 8: Brain; 9: Uterus)at 1:200 dilution.

Anti-APOBR / APOB48R Antibody (aa780-1088, clone 1B1) - LS-C340182 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1B1

IHC of paraffin-embedded Human tonsil using anti-APOBR mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

APOB48R Antibody (2D7) - H00055911-M03 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2D7

Immunohistochemistry-Paraffin: APOB48R Antibody (2D7) [H00055911-M03] - Analysis of monoclonal antibody to APOB48R on formalin-fixed paraffin-embedded human prostate. Antibody concentration 1.5 ug/ml

APOB48R Antibody - NBP1-90130 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry: APOB48R Antibody [NBP1-90130] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.

APOB48R Antibody - NBP1-90129 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry: APOB48R Antibody [NBP1-90129] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells and peripheral leukocytes.

APOB48R Polyclonal Antibody - bs-6336R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

$Antigen: bs-6336P, 0.2ug/100ul \\nPrimary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; \\nSecondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; \\nTMB staining; Read the data in Microplate Reader by 450nm\\n$

ANTI-APOB48R (CENTER) antibody produced in rabbit - SAB1305210 from Sigma-Aldrich

Prices	$326.00
Sizes	40 tst
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-APOB48R (Center): <B>Cat. No. SAB1305210</B>: APOB48R Antibody (Center) western blot analysis in A549 cell line lysates (35 μg/lane).

Anti-APOBR antibody produced in rabbit - HPA042093 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-APOBR: <B>Cat. No. HPA042093</B>: Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in glandular cells and peripheral leukocytes.

Monoclonal Anti-APOB48R antibody produced in mouse - WH0055911M3 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2D7

<B>Immunoblotting</B><BR/>Monoclonal Anti-APOB48R, <B>Cat. No. WH0055911M3</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37.11 kDa using immunogen protein lysate.

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