BPTF

Gene Symbol BPTF
Entrez Gene 2186
Alt Symbol FAC1, FALZ, NURF301
Species Human
Gene Type protein-coding
Description bromodomain PHD finger transcription factor
Other Description bromodomain and PHD domain transcription factor|bromodomain and PHD finger-containing transcription factor|fetal Alz-50 clone 1 protein|fetal Alz-50 reactive clone 1|fetal Alzheimer antigen|nucleosome remodeling factor, large subunit|nucleosome-remodeling factor subunit BPTF
Swissprots Q6NX67 Q7Z7D6 Q12830 Q9UIG2
Accessions EAW89038 EAW89039 Q12830 AB032251 BAA89208 AK022081 AK022570 AK025776 AK027184 BAB15686 AK293224 BAG56763 AK296256 BAG58970 AK297281 BAG59752 AL833375 AY282495 AAP22284 BC037422 BC039881 BC050566 AAH50566 BC067234 AAH67234 BE464864 BQ716216 BU169920 BU176205 CF135401 CV809604 U05237 AAA97522 XM_005257150 XP_005257207 XM_005257151 XP_005257208 XM_005257152 XP_005257209 XM_005257153 XP_005257210 XM_005257154 XP_005257211 XM_005257155 XP_005257212 XM_005257156 XP_005257213 XM_005257157 XP_005257214 XM_005257158 XP_005257215 XM_005257159 XP_005257216 XM_005257160 XP_005257217 XM_005257161 XP_005257218 XM_005257162 XP_005257219 XM_011524520 XP_011522822 XM_011524521 XP_011522823 XM_011524522 XP_011522824 XM_011524523 XP_011522825 XM_011524524 XP_011522826 XM_011524525 XP_011522827 XM_011524526 XP_011522828 NM_004459 NP_004450 NM_182641 NP_872579
Function Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.
Subcellular Location Cytoplasm. Nucleus. Note=In brains of Alzheimer disease patients, present in a subset of amyloid- containing plaques.
Tissue Specificity Ubiquitously expressed, with highest levels in testis. Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex (at protein level). {ECO:0000269|PubMed:10662542, ECO:0000269|PubMed:10727212, ECO:0000269|PubMed:7621746, ECO:0000269|PubMed:9225734}.

BPTF (H-42) - sc-98404 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BPTF (H-42): sc-98404. Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing nuclear and cytoplasmic staining of respiratory epithelial cells.

BPTF (N-18) - sc-107456 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BPTF (2343C3a) - sc-81088 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
BPTF (2343C3a): sc-81088 Western Blot analysis of human recombinant BPTF fusion protein.

Anti-BPTF / FALZ antibody - ab72036 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling BPTF / FALZ with ab72036 at 1/200 (1µg/ml). Detection: DAB.

Anti-BPTF / FALZ antibody - ab99399 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab99399, at 1/250 dilution, staining BPTF / FALZ in formalin-fixed, paraffin-embedded Human breast carcinoma by Immunohistochemistry. Detection: DAB staining.

Anti-BPTF / FALZ antibody [2343C3a] - ab54356 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2343C3a
Anti-BPTF / FALZ antibody [2343C3a] (ab54356) + immunising recombinant protein fragment.

Anti-FAC1 / BPTF Antibody - LS-C77296 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-FAC1 / BPTF Antibody (aa1350-1400) - LS-C77297 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FAC1 / BPTF Antibody (clone 2343C3a) - LS-C184489 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2343C3a

Anti-FAC1 / BPTF Antibody (clone 2343C3a) - LS-C342530 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2343C3a
Western blot analysis of immunized recombinant protein, using anti-FALZ monoclonal antibody.

Anti-FAC1 / BPTF Antibody (aa1350-1400) - LS-C286732 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
FFPE section of human colon carcinoma. LS-C286732 used at a dilution of 1:250.

Anti-FAC1 / BPTF Antibody (aa1350-1400) - LS-C287806 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human FALZ/BPTF by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-FALZ/BPTF used at a dilution of 1:200 (1 Detection: DAB.

Anti-FAC1 / BPTF Antibody (clone 2F10) IHC-plus™ - LS-B10731 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 2F10
Anti-FAC1 / BPTF antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10731 dilution 1:50.

BPTF/FALZ Antibody - NB100-41418 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BPTF/FALZ Antibody [NB100-41418] - Detection of Human FALZ/BPTF by Western Blot. Samples: Whole cell lysate (15 and 50 ug) from HeLa cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-FALZ/BPTF antibody NB100-41418 used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

BPTF/FALZ Antibody - NBP1-84756 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: BPTF/FALZ Antibody [NBP1-84756] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.

BPTF/FALZ Antibody (2F10) - NBP2-37608 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F10

BPTF/FALZ Polyclonal Antibody - bs-11641R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-BPTF/FALZ Polyclonal Antibody, Unconjugated (bs-11641R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

BPTF/FALZ Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11641R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BPTF/FALZ Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11641R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BPTF/FALZ Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11641R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BPTF/FALZ Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11641R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BPTF/FALZ Polyclonal Antibody, Cy3 Conjugated - bs-11641R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BPTF/FALZ Polyclonal Antibody, Cy5 Conjugated - bs-11641R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BPTF/FALZ Polyclonal Antibody, Cy5.5 Conjugated - bs-11641R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BPTF/FALZ Polyclonal Antibody, Cy7 Conjugated - bs-11641R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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