BPTF

Gene Symbol	BPTF
Entrez Gene	2186
Alt Symbol	FAC1, FALZ, NURF301
Species	Human
Gene Type	protein-coding
Description	bromodomain PHD finger transcription factor
Other Description	bromodomain and PHD domain transcription factor|bromodomain and PHD finger-containing transcription factor|fetal Alz-50 clone 1 protein|fetal Alz-50 reactive clone 1|fetal Alzheimer antigen|nucleosome remodeling factor, large subunit|nucleosome-remodeling factor subunit BPTF
Swissprots	Q6NX67 Q7Z7D6 Q12830 Q9UIG2
Accessions	EAW89038 EAW89039 Q12830 AB032251 BAA89208 AK022081 AK022570 AK025776 AK027184 BAB15686 AK293224 BAG56763 AK296256 BAG58970 AK297281 BAG59752 AL833375 AY282495 AAP22284 BC037422 BC039881 BC050566 AAH50566 BC067234 AAH67234 BE464864 BQ716216 BU169920 BU176205 CF135401 CV809604 U05237 AAA97522 XM_005257150 XP_005257207 XM_005257151 XP_005257208 XM_005257152 XP_005257209 XM_005257153 XP_005257210 XM_005257154 XP_005257211 XM_005257155 XP_005257212 XM_005257156 XP_005257213 XM_005257157 XP_005257214 XM_005257158 XP_005257215 XM_005257159 XP_005257216 XM_005257160 XP_005257217 XM_005257161 XP_005257218 XM_005257162 XP_005257219 XM_011524520 XP_011522822 XM_011524521 XP_011522823 XM_011524522 XP_011522824 XM_011524523 XP_011522825 XM_011524524 XP_011522826 XM_011524525 XP_011522827 XM_011524526 XP_011522828 NM_004459 NP_004450 NM_182641 NP_872579
Function	Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.
Subcellular Location	Cytoplasm. Nucleus. Note=In brains of Alzheimer disease patients, present in a subset of amyloid- containing plaques.
Tissue Specificity	Ubiquitously expressed, with highest levels in testis. Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex (at protein level). {ECO:0000269|PubMed:10662542, ECO:0000269|PubMed:10727212, ECO:0000269|PubMed:7621746, ECO:0000269|PubMed:9225734}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BPTF / FALZ protein fragment - ab195161 from Abcam Category Protein Prices $742.00 Sizes 100 µg Source E. coli Species Human

Human BPTF / FALZ protein fragment - ab176966 from Abcam Category Protein Prices $248.00 Sizes 20 µg Source E. coli Species Human

Human BPTF / FALZ protein fragment - ab198097 from Abcam Category Protein Prices $359.00 Sizes 100 µg Source E. coli Species Human

Phospho-FALZS77-Antibody-Blocking-peptide - BP3629a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Recombinant BPTF / FALZ (2791-2911) protein - 31447 from ActiveMotif Category Protein Prices $395.00, $2,600.00 Sizes 100 μg, 1 mg Source E. coli Species Human

Recombinant Human BPTF, GST-tagged - BPTF-156H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human BPTF, His&FLAG-tagged - BPTF-33H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Nucleosome-remodeling factor subunit BPTF(BPTF) ,partial - CSB-YP614258HU CSB-EP614258HU CSB-BP614258HU CSB-MP614258HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BPTF bromodomain (2796-2907 aa) (GST-tagged), Human recombinant - 7662-20 from Biovision Category Protein Prices $175.00 Sizes 20 μg Source E. coli Species Human

BPTF bromodomain (2796-2907 aa) (GST-tagged), Human recombinant - 7662-100 from Biovision Category Protein Prices $595.00 Sizes 100 μg Source E. coli Species Human

Recombinant Human BPTF protein, GST-tagged - BPTF-80H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human BPTF protein, His-tagged - BPTF-81H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human BPTF protein, GST-tagged - BPTF-82H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human BPTF protein, His-tagged - BPTF-83H from Creative Biomart Category Protein Source E. coli Species Human

BPTF/FALZ Recombinant Protein Antigen - NBP1-84756PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BPTF Peptide, Human - M34GP01515H from Creative Peptides Category Peptide Source Synthetic. Species Human

BPTF bromodomain (2796-2907 aa) (GST-tagged), Human recombinant - 7662 from Biovision Category Protein Prices $175.00, $595.00 Sizes 20 μg, 100 μg Source E. coli Species Human

BPTF/FALZ Recombinant Protein Antigen - NBP2-57567PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BPTF bromodomain, Recombinant Protein - MBS844552 from MyBioSource Category Protein Prices $235.00, $695.00 Sizes 20 µg, 100 µg Source E Coli

Nucleosome-remodeling factor subunit BPTF (BPTF), partial, Recombinant Protein - MBS1471143 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

BPTF fusion protein - Ag27780 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

BPTF fusion protein - Ag27761 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

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