| Gene Symbol |
FANCC
|
| Entrez Gene |
2176
|
| Alt Symbol |
FA3, FAC, FACC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Fanconi anemia, complementation group C
|
| Other Description |
Fanconi anemia group C protein
|
| Swissprots |
Q00597 B1ALR8
|
| Accessions |
AAA53104 AAO26042 EAW92626 EAW92627 EAW92628 EAW92629 Q00597 AI280997 AK222871 AK304887 BAG65624 AK310599 AK312548 AU132608 BC006303 BC015748 AAH15748 BC041030 CB052780 DB445119 DQ895422 ABM86348 EU176333 ABW03784 S64600 X66893 CAA47347 X66894 CAA47348 XM_005251802 XP_005251859 XM_006717001 XP_006717064 XM_006717002 XP_006717065 XM_006717004 XP_006717067 XM_011518365 XP_011516667 XM_011518366 XP_011516668 XM_011518367 XP_011516669 NM_000136 NP_000127 NM_001243743 NP_001230672 NM_001243744 NP_001230673
|
| Function |
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. {ECO:0000269|PubMed:11520787}.
|
| Subcellular Location |
Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Fanconi anemia pathway
|
![Western Blot: FANCC Overexpression Lysate (Adult Normal) [NBL1-10587] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FANCC.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8279_FANCC%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10587-img0002.jpg)