Gene Symbol | FANCC |
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Entrez Gene | 2176 |
Alt Symbol | FA3, FAC, FACC |
Species | Human |
Gene Type | protein-coding |
Description | Fanconi anemia, complementation group C |
Other Description | Fanconi anemia group C protein |
Swissprots | Q00597 B1ALR8 |
Accessions | AAA53104 AAO26042 EAW92626 EAW92627 EAW92628 EAW92629 Q00597 AI280997 AK222871 AK304887 BAG65624 AK310599 AK312548 AU132608 BC006303 BC015748 AAH15748 BC041030 CB052780 DB445119 DQ895422 ABM86348 EU176333 ABW03784 S64600 X66893 CAA47347 X66894 CAA47348 XM_005251802 XP_005251859 XM_006717001 XP_006717064 XM_006717002 XP_006717065 XM_006717004 XP_006717067 XM_011518365 XP_011516667 XM_011518366 XP_011516668 XM_011518367 XP_011516669 NM_000136 NP_000127 NM_001243743 NP_001230672 NM_001243744 NP_001230673 |
Function | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. {ECO:0000269|PubMed:11520787}. |
Subcellular Location | Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Fanconi anemia pathway |
FANCC (C-14) - sc-18110 from Santa Cruz Biotechnology
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FANCC (H-300) - sc-28216 from Santa Cruz Biotechnology
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FANCC (P-17) - sc-23777 from Santa Cruz Biotechnology
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FANCC (V-20) - sc-18109 from Santa Cruz Biotechnology
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Anti-FANCC antibody - ab5065 from Abcam
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Anti-FANCC antibody - ab97575 from Abcam
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Anti-FANCC antibody - ab54631 from Abcam
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Anti-FANCC antibody - ab189089 from Abcam
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Anti-FANCC antibody - ab102788 from Abcam
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Anti-FANCC antibody - C-terminal - ab180767 from Abcam
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Anti-FANCC antibody - N-terminal - ab157142 from Abcam
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Anti-FANCC Antibody (C-Terminus) - LS-C65891 from LifeSpan Bioscience
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Anti-FANCC Antibody - LS-C121790 from LifeSpan Bioscience
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Anti-FANCC Antibody (aa1-101) - LS-C128956 from LifeSpan Bioscience
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Anti-FANCC Antibody (aa1-558) - LS-C128957 from LifeSpan Bioscience
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Anti-FANCC Antibody (C-Terminus, clone 8F3, Biotin) - LS-C142660 from LifeSpan Bioscience
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Anti-FANCC Antibody (C-Terminus, clone 8F3, DY488) - LS-C142662 from LifeSpan Bioscience
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Anti-FANCC Antibody (aa450-558) - LS-C49030 from LifeSpan Bioscience
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Anti-FANCC Antibody (C-Terminus, clone 8F3, DY650) - LS-C142661 from LifeSpan Bioscience
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Anti-FANCC Antibody (C-Terminus, clone 8F3, HRP) - LS-C142663 from LifeSpan Bioscience
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Anti-FANCC Antibody (C-Terminus, clone 8F3) - LS-C142659 from LifeSpan Bioscience
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Anti-FANCC Antibody (C-Terminus) - LS-C141541 from LifeSpan Bioscience
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Anti-FANCC Antibody (C-Terminus, clone 8F3, DY550) - LS-C142664 from LifeSpan Bioscience
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Anti-FANCC Antibody - LS-C192772 from LifeSpan Bioscience
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Anti-FANCC Antibody (aa527-555, APC) - LS-C214128 from LifeSpan Bioscience
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