| Gene Symbol | FANCC |
|---|---|
| Entrez Gene | 2176 |
| Alt Symbol | FA3, FAC, FACC |
| Species | Human |
| Gene Type | protein-coding |
| Description | Fanconi anemia, complementation group C |
| Other Description | Fanconi anemia group C protein |
| Swissprots | Q00597 B1ALR8 |
| Accessions | AAA53104 AAO26042 EAW92626 EAW92627 EAW92628 EAW92629 Q00597 AI280997 AK222871 AK304887 BAG65624 AK310599 AK312548 AU132608 BC006303 BC015748 AAH15748 BC041030 CB052780 DB445119 DQ895422 ABM86348 EU176333 ABW03784 S64600 X66893 CAA47347 X66894 CAA47348 XM_005251802 XP_005251859 XM_006717001 XP_006717064 XM_006717002 XP_006717065 XM_006717004 XP_006717067 XM_011518365 XP_011516667 XM_011518366 XP_011516668 XM_011518367 XP_011516669 NM_000136 NP_000127 NM_001243743 NP_001230672 NM_001243744 NP_001230673 |
| Function | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. {ECO:0000269|PubMed:11520787}. |
| Subcellular Location | Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic. |
| Tissue Specificity | Ubiquitous. |
| Top Pathways | Fanconi anemia pathway |