Gene Symbol | IL17A |
---|---|
Entrez Gene | 3605 |
Alt Symbol | CTLA8, IL-17, IL-17A, IL17 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 17A |
Other Description | CTLA-8|cytotoxic T-lymphocyte-associated antigen 8|cytotoxic T-lymphocyte-associated protein 8|interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)|interleukin-17A |
Swissprots | Q5T2P0 Q16552 |
Accessions | AAR23263 AAV41220 CAL44889 CAV28580 CBH19852 CCA63959 CCB07363 EAX04362 Q16552 BC066251 AAH66251 BC066252 AAH66252 BC066253 AAH66253 BC067503 AAH67503 BC067504 AAH67504 BC067505 AAH67505 HM535222 ADJ56412 HQ447533 ADQ32019 U32659 AAC50341 Z58820 CAA91233 NM_002190 NP_002181 |
Function | Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. |
Subcellular Location | Secreted. |
Tissue Specificity | Restricted to activated memory T-cells. |
Top Pathways | Cytokine-cytokine receptor interaction, Rheumatoid arthritis, Inflammatory bowel disease (IBD) |
IL-17 CRISPR/Cas9 KO Plasmid (h) - sc-400293 from Santa Cruz Biotechnology
|
||||||||
IL-17 HDR Plasmid (h) - sc-400293-HDR from Santa Cruz Biotechnology
|
||||||||
IL-17 Double Nickase Plasmid (h) - sc-400293-NIC from Santa Cruz Biotechnology
|
||||||||
IL-17 Double Nickase Plasmid (h2) - sc-400293-NIC-2 from Santa Cruz Biotechnology
|
||||||||
IL-17 CRISPR Activation Plasmid (h) - sc-400293-ACT from Santa Cruz Biotechnology
|
||||||||
IL-17 CRISPR Activation Plasmid (h2) - sc-400293-ACT-2 from Santa Cruz Biotechnology
|
||||||||
IL-17 Lentiviral Activation Particles (h) - sc-400293-LAC from Santa Cruz Biotechnology
|
||||||||
IL-17 Lentiviral Activation Particles (h2) - sc-400293-LAC-2 from Santa Cruz Biotechnology
|
||||||||
IL-17 siRNA (h) - sc-39649 from Santa Cruz Biotechnology
|
||||||||
IL-17 shRNA Plasmid (h) - sc-39649-SH from Santa Cruz Biotechnology
|
||||||||
IL-17 shRNA (h) Lentiviral Particles - sc-39649-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN10575 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10575 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR09055 from Sigma-Aldrich
|
||||||||
IL17A siRNA (Human) - CRH2412 from Cohesion Biosciences
|
||||||||
IL17A - MBS8235619 from MyBioSource
|
||||||||
shRNA set against Human IL17A (NM_002190.2) - SHH318293 from Creative biogene
|
||||||||
shRNA set against Human IL17A(NM_002190.2) - SHL171184 from Creative biogene
|
||||||||
IL-17 CRISPR/Cas9 KO Plasmid (h2) - sc-400293-KO-2 from Santa Cruz Biotechnology
|
||||||||
IL-17 HDR Plasmid (h2) - sc-400293-HDR-2 from Santa Cruz Biotechnology
|
||||||||
Human IL17A siRNA - orb262914 from Biorbyt
|
||||||||
IL17A shRNA Plasmid (Human) - CHH2412 from Cohesion Biosciences
|
||||||||
IL17A miRNA 3'UTR clone - MiUTR1H-04877 from Creative biogene
|