Gene Symbol |
IL17A
|
Entrez Gene |
3605
|
Alt Symbol |
CTLA8, IL-17, IL-17A, IL17
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
interleukin 17A
|
Other Description |
CTLA-8|cytotoxic T-lymphocyte-associated antigen 8|cytotoxic T-lymphocyte-associated protein 8|interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)|interleukin-17A
|
Swissprots |
Q5T2P0 Q16552
|
Accessions |
AAR23263 AAV41220 CAL44889 CAV28580 CBH19852 CCA63959 CCB07363 EAX04362 Q16552 BC066251 AAH66251 BC066252 AAH66252 BC066253 AAH66253 BC067503 AAH67503 BC067504 AAH67504 BC067505 AAH67505 HM535222 ADJ56412 HQ447533 ADQ32019 U32659 AAC50341 Z58820 CAA91233 NM_002190 NP_002181
|
Function |
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Restricted to activated memory T-cells.
|
Top Pathways |
Cytokine-cytokine receptor interaction, Rheumatoid arthritis, Inflammatory bowel disease (IBD)
|