Gene Symbol | IL17A |
---|---|
Entrez Gene | 3605 |
Alt Symbol | CTLA8, IL-17, IL-17A, IL17 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 17A |
Other Description | CTLA-8|cytotoxic T-lymphocyte-associated antigen 8|cytotoxic T-lymphocyte-associated protein 8|interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)|interleukin-17A |
Swissprots | Q5T2P0 Q16552 |
Accessions | AAR23263 AAV41220 CAL44889 CAV28580 CBH19852 CCA63959 CCB07363 EAX04362 Q16552 BC066251 AAH66251 BC066252 AAH66252 BC066253 AAH66253 BC067503 AAH67503 BC067504 AAH67504 BC067505 AAH67505 HM535222 ADJ56412 HQ447533 ADQ32019 U32659 AAC50341 Z58820 CAA91233 NM_002190 NP_002181 |
Function | Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. |
Subcellular Location | Secreted. |
Tissue Specificity | Restricted to activated memory T-cells. |
Top Pathways | Cytokine-cytokine receptor interaction, Rheumatoid arthritis, Inflammatory bowel disease (IBD) |