CXCL8

Gene Symbol	CXCL8
Entrez Gene	3576
Alt Symbol	GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
Species	Human
Gene Type	protein-coding
Description	chemokine (C-X-C motif) ligand 8
Other Description	T-cell chemotactic factor|alveolar macrophage chemotactic factor I|beta endothelial cell-derived neutrophil activating peptide|beta-thromboglobulin-like protein|emoctakin|granulocyte chemotactic protein 1|interleukin 8|interleukin-8|lung giant cell carcinoma-derived chemotactic protein|lymphocyte derived neutrophil activating peptide|monocyte-derived neutrophil chemotactic factor|monocyte-derived neutrophil-activating peptide|neutrophil-activating peptide 1|small inducible cytokine subfamily B, member 8|tumor necrosis factor-induced gene 1
Swissprots	Q6LAE6 P10145 Q9C077 Q6FGF6 Q9UCR9 Q9UCR8 Q9UCE1 B2R4L8 Q96RG6 Q9UCS0
Accessions	AAA59158 AAK60276 BAA03245 CBK51144 CBX54344 EAX05687 EAX05688 EAX05689 P10145 AJ227913 AK131067 AK311874 BAG34815 BC013615 AAH13615 BG497712 BT007067 AAP35730 CR542151 CAG46948 DQ890564 ABM92181 DQ893727 ABM84653 M17017 AAA35611 M23344 AAA74722 M26383 AAA36323 Y00787 CAA68742 Z11686 CAA77745 NM_000584 NP_000575
Function	IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. {ECO:0000269|PubMed:11978786, ECO:0000269|PubMed:2145175, ECO:0000269|PubMed:2212672}.
Subcellular Location	Secreted.
Top Pathways	Malaria, Legionellosis, Salmonella infection, Influenza A, Non-alcoholic fatty liver disease (NAFLD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active dog IL8 full length protein - ab200269 from Abcam Category Protein Prices $107.00 Sizes 5 µg Source E. coli Species Dog

Active human IL8 full length protein - ab192140 from Abcam Category Protein Prices $192.00 Sizes 25 µg Source E. coli Species Human

Active human IL8 full length protein - ab198561 from Abcam Category Protein Prices $300.00 Sizes 25 µg Source E. coli Species Human

Active human IL8 full length protein - ab73858 from Abcam Category Protein Prices $200.00 Sizes 25 µg Source E. coli Species Human

Active human IL8 full length protein - ab9631 from Abcam Category Protein Prices $257.00 Sizes 25 µg Source E. coli Species Human

Active pig IL8 full length protein - ab73809 from Abcam Category Protein Source E. coli Species Pig

Cat IL8 full length protein - ab90393 from Abcam Category Protein Prices $309.00 Sizes 25 µg Source Yeast Species Cat

Cow IL8 full length protein - ab87522 from Abcam Category Protein Prices $252.00 Sizes 25 µg Source Yeast Species Bovine

Dog IL8 protein fragment - ab87500 from Abcam Category Protein Prices $252.00 Sizes 25 µg Source Yeast Species Dog

Guinea pig IL8 full length protein - ab117225 from Abcam Category Protein Prices $345.00 Sizes 25 µg Source Yeast Species Guinea Pig

Human CXCL8/IL-8 full length protein - ab194024 from Abcam Category Protein Source Mammalian Species Human

Human IL8 full length protein - ab167998 from Abcam Category Protein Source Yeast Species Human

Human IL8 full length protein - ab191925 from Abcam Category Protein Source HEK 293 cells Species Human

Human IL8 full length protein - ab175169 from Abcam Category Protein Source Synthetic Species Human

Human IL8 full length protein - ab176073 from Abcam Category Protein Source Synthetic Species Human

Human IL8 protein fragment - ab49839 from Abcam Category Protein Source E. coli Species Human

Human IL8 protein fragment - ab53373 from Abcam Category Protein Source E. coli Species Human

Human IL8 protein fragment - ab51095 from Abcam Category Protein Source E. coli Species Human

IL8 full length protein - ab117214 from Abcam Category Protein Source Yeast

Pig IL8 full length protein - ab60259 from Abcam Category Protein Source E. coli Species Pig

Pig IL8 full length protein - ab90394 from Abcam Category Protein Source Yeast Species Pig

Sheep IL8 full length protein - ab169712 from Abcam Category Protein Source Yeast Species Sheep

IL8 / Interleukin 8 Antibody Blocking Peptide - LS-E9674 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CXCL8/IL-8 Protein - NBP2-34905 from Novus Biologicals Category Protein Prices $69.00, $149.00, $2,669.00 Sizes 5 µg, 25 µg, 1 mg Source E. coli Species Human

Recombinant Human CXCL8/IL-8 Protein - NBP2-34907 from Novus Biologicals Category Protein Prices $69.00, $149.00, $2,669.00 Sizes 5 µg, 25 µg, 1 mg Source E. coli Species Human

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