TNNI1

Gene Symbol TNNI1
Entrez Gene 7135
Alt Symbol SSTNI, TNN1
Species Human
Gene Type protein-coding
Description troponin I type 1 (skeletal, slow)
Other Description troponin I, slow skeletal muscle|troponin I, slow-twitch isoform
Swissprots Q86T57 Q6FGW1 P19237 Q96DT9 Q6FGS7 Q6ICU2 A8MSJ0 A6NEH3 Q659A5
Accessions AAC14461 EAW91365 EAW91366 EAW91367 EAW91368 P19237 AJ315823 CAC44240 AK123965 BAG53988 AK223588 BAD97308 AK311896 BAG34837 AL831820 CAD38534 AL831975 CAH56221 AL832006 AM392810 CAL37688 BC012600 AAH12600 BC012601 AAH12601 BI825503 BX510903 CAD91135 CR450301 CAG29297 CR541996 CAG46793 CR542030 CAG46827 DQ892818 ABM83744 DQ896064 ABM87063 J04760 AAA61228 NM_003281 NP_003272
Function Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Tissue Specificity Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes. {ECO:0000269|PubMed:2365354, ECO:0000269|PubMed:8144655}.

Troponin I-SS (E-13) - sc-30488 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Troponin I-SS (E-13): sc-30488. Western blot analysis of Troponin I-SS expression in rat skeletal muscle tissue extract.

Troponin I-SS (D-13) - sc-30490 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Troponin I-SS (D-13): sc-30490. Western blot analysis of Troponin I-SS expression in rat skeletal muscle tissue extract.

Troponin I-SS (C-19) - sc-8119 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Troponin I-SS (C-19): sc-8119. Western blot analysis of Troponin I-SS expression in rat skeletal muscle tissue extract.

Troponin I-SS (H-51) - sc-20645 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Troponin I-SS (H-51): sc-20645. Western blot analysis of Troponin I-SS expression in rat skeletal muscle tissue extract.

Anti-TNNI1 antibody - ab85087 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of TNNI1 expression in formalin fixed, paraffin embedded skeletal muscle using ab85087 at a 1/100 dilution. Note cytoplasmic staining.

Anti-TNNI1 antibody - ab126193 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-TNNI1 antibody (ab126193) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-TNNI1 antibody - ab174752 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-TNNI1 antibody (ab174752) at 0.2 µg/ml + Human skeletal muscle lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-TNNI1 antibody - ab97898 from Abcam

Host Sheep
Clonality Polyclonal

Anti-TNNI1 antibody [12F10] - ab8293 from Abcam

Prices $380.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 12F10
All lanes : Anti-TNNI1 antibody [12F10] (ab8293) at 1 µg/mlLane 1 : 40ug human muscle lysate (whole tissue)Lane 2 : 40ug human muscle lysate (whole tissue)Lane 3 : 40ug human muscle lysate (whole tissue)Lane 4 : 40ug human muscle lysate (whole tissue)Lane 5 : 40ug human muscle lysate (whole tissue)Lane 6 : 40ug human muscle lysate (whole tissue)Lane 7 : 40ug rat adipose lysate (whole tissue)SecondaryHRP donkey anti-mouse HRPdeveloped using the ECL techniquePerformed under non-reducing conditions.Observed band size : 22 kDa (why is the actual band size different from the predicted?)Exposure time :  5 secondsThis image is courtesy of an anonymous AbreviewSee Abreview

Anti-TNNI1 antibody [AT36E7] - ab171650 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT36E7
Lane 1 :  Anti-TNNI1 antibody [AT36E7] (ab171650) at 1/500 dilutionLane 2 :  Anti-TNNI1 antibody [AT36E7] (ab171650) at 1/1000 dilutionLane 3 :  Anti-TNNI1 antibody [AT36E7] (ab171650) at 1/5000 dilutionLane 1 : Mouse muscle lysateLane 2 : Mouse muscle lysateLane 3 : Mouse muscle lysateLysates/proteins at 40 µg per lane.SecondaryGoat anti-mouse conjugated to HRPdeveloped using the ECL technique

Anti-TNNI1 antibody [EPR17120] - ab202422 from Abcam

Prices $99.00, $347.00
Sizes 10 µl, 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR17120
All lanes : Anti-TNNI1 antibody [EPR17120] (ab202422) at 1/10000 dilutionLane 1 : Human fetal heart lysateLane 2 : Human fetal kidney lysateLane 3 : U-87 MG (Human glioblastoma-astrocytoma epithelial cell line) cell lysateLane 4 : HepG2 (Human liver hepatocellular carcinoma) cell lysateLysates/proteins at 10 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/50000 dilution

Anti-TNNI1 antibody - N-terminal - ab174761 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-TNNI1 antibody - N-terminal (ab174761) at 0.03 µg/ml + Human Skeletal Muscle lysate at 35 µgdeveloped using the ECL technique

Anti-Troponin I fast + slow skeletal muscle antibody [12F10] - ab110132 from Abcam

Prices $407.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 12F10
ab110132 at 10 µg/ml staining Troponin I fast + slow skeletal muscle in Formalin-Fixed, Paraffin-Embedded Human skeletal muscle tissue by Immunohistochemistry. Detection utilised biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Anti-Troponin I fast + slow skeletal muscle antibody [7G2] (HRP) - ab24464 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 7G2

Anti-TNNI1 Antibody (aa1-187) - LS-C296811 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant TNNI1.

Anti-TNNI1 Antibody (aa1-187) - LS-C292529 from LifeSpan Bioscience

Prices $445.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Western blot of recombinant TNNI1.

Anti-TNNI1 Antibody (aa1-187) - LS-C296812 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant TNNI1.

Anti-TNNI1 Antibody (aa2-15) - LS-C186612 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
TNNI1 antibody (0.03 ug/ml) staining of Human Skeletal Muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-TNNI1 Antibody (clone 8H8) - LS-C340307 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8H8
IHC of paraffin-embedded Human muscle tissue using anti-TNNI1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-TNNI1 Antibody (N-Terminus) IHC-plus™ - LS-B3547 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TNNI1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3547 concentration 5 ug/ml.

Anti-TNNI1 Antibody (aa111-160) - LS-C31902 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-TNNI1 Antibody (N-Terminus) - LS-C137076 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TNNI1 Antibody (aa1-187, Biotin) - LS-C299287 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-TNNI1 Antibody (aa1-187, Biotin) - LS-C300885 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNNI1 Antibody (aa1-187, Biotin) - LS-C300886 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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