Gene Symbol | HIST1H2BB |
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Entrez Gene | 3018 |
Alt Symbol | H2B.1, H2B/f, H2BFF |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2bb |
Other Description | H2B histone family, member F|histone 1, H2bb|histone H2B type 1-B|histone H2B.1|histone H2B.f |
Swissprots | P33778 Q4KN36 |
Accessions | AAN06685 CAA40406 EAW55513 P33778 BC096728 AAH96728 EU446966 ABZ92495 NM_021062 NP_066406 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone cluster 1 H2BB CRISPR/Cas9 KO Plasmid (h) - sc-410814 from Santa Cruz Biotechnology
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Histone cluster 1 H2BB HDR Plasmid (h) - sc-410814-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H2BB Double Nickase Plasmid (h) - sc-410814-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H2BB Double Nickase Plasmid (h2) - sc-410814-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BB CRISPR Activation Plasmid (h) - sc-410814-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H2BB CRISPR Activation Plasmid (h2) - sc-410814-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BB Lentiviral Activation Particles (h) - sc-410814-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H2BB Lentiviral Activation Particles (h2) - sc-410814-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BB siRNA (h) - sc-105472 from Santa Cruz Biotechnology
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Histone cluster 1 H2BB shRNA Plasmid (h) - sc-105472-SH from Santa Cruz Biotechnology
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Histone cluster 1 H2BB shRNA (h) Lentiviral Particles - sc-105472-V from Santa Cruz Biotechnology
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Histone H2B type 1B RNAi - H00003018-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN10069 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10069 from Sigma-Aldrich
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HIST1H2BB siRNA (Human) - CRH2052 from Cohesion Biosciences
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HIST1H2BB - MBS8233590 from MyBioSource
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shRNA set against Human HIST1H2BB (NM_021062.2) - SHH312557 from Creative biogene
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shRNA set against Human HIST1H2BB(NM_021062.2) - SHH122267 from Creative biogene
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HIST1H2BB shRNA Plasmid (Human) - CHH2052 from Cohesion Biosciences
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HIST1H2BB miRNA 3'UTR clone - MiUTR1H-04531 from Creative biogene
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